Literature DB >> 646143

Antispermatogenic effect of aspirin and its prevention by prostaglandin E2.

N M Biswas, S Sanyal, P B Patra.   

Abstract

Aspirin treatment causes a decrease in Leydig cell function, change in Sertoli cell morphology and a subsequent decrease in Spermatid count. Administration of Prostaglandin E2 prevents the effect of Aspirin on the Sertoli cell morphology and Spermatid degeneration without significant improvement of the Leydig cell function. On the basis of these findings, a possible relationship between Prostaglandin and testicular spermatogenesis has been discussed.

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Year:  1978        PMID: 646143     DOI: 10.1111/j.1439-0272.1978.tb01328.x

Source DB:  PubMed          Journal:  Andrologia        ISSN: 0303-4569            Impact factor:   2.775


  2 in total

1.  Role of seminal prostaglandins in male fertility. II. Effects of prostaglandin synthesis inhibition on spermatogenesis in man.

Authors:  D Conte; M Nordio; F Romanelli; F Manganelli; P Giovenco; F Dondero; A Isidori
Journal:  J Endocrinol Invest       Date:  1985-08       Impact factor: 4.256

2.  Association Between Male Use of Pain Medication and Fecundability.

Authors:  Amelia K Wesselink; Kathryn A Bresnick; Elizabeth E Hatch; Kenneth J Rothman; Ellen M Mikkelsen; Tanran R Wang; Krista F Huybrechts; Lauren A Wise
Journal:  Am J Epidemiol       Date:  2020-11-02       Impact factor: 4.897

  2 in total

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