Lithium carbonate toxicity. Acneform eruption and other manifestation.

Manifestations of lithium carbonate toxicity include acneform eruptions, sinus node dysfunction, hyperparathyroidism, hypothyroidism, thyrotoxicosis, extrapyramidal side effects, and renal toxicity, which may present as nephrogenous diabetes insipidus. This report concerns a patient with a toxic reaction to lithium carbonate. The patient initially had acneform lesions, hypoglycemia, hypothyroidism, and nephrogenous diabetes insipidus. Features of lithium carbonate-induced acneform eruptions are emphasized. Renal toxicity from a lithium carbonate overdose is common, and the hazards of prescribing potentially nephrotoxic drugs to such a patient are stressed.