Literature DB >> 6459764

Comparative efficacy of piperacillin and penicillin G in treatment of gonococcal urethritis.

S J Landis, R Ramphal, B J Mansheim, K H Rand, J W Shands.   

Abstract

The comparative efficacy of 2 g of piperacillin and 4.8 X 10(6) U of penicillin G in the treatment of uncomplicated gonococcal urethritis was assessed in a randomized prospective study. Sixty-five evaluable patients received piperacillin, and 55 received penicillin G. All patients received either therapy were cured of gonorrhea. We conclude that piperacillin is as efficacious as aqueous procaine penicillin G in the therapy of uncomplicated gonococcal urethritis.

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Year:  1981        PMID： 6459764      PMCID： PMC181777          DOI： 10.1128/AAC.20.5.693

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  3 in total

1.  In vitro antimicrobial activity of piperacillin and seven other beta-lactam antibiotics against Neisseria gonorrhoeae and Haemophilus influenzae, including beta-lactamase producing strains.

Authors:  C Thornsberry; C N Baker; R N Jones
Journal:  J Antimicrob Chemother       Date:  1979-03       Impact factor: 5.790

2.  Piperacillin therapy for serious bacterial infections.

Authors:  D J Winston; W Murphy; L S Young; W L Hewitt
Journal:  Am J Med       Date:  1980-08       Impact factor: 4.965

3.  Piperacillin: human pharmacokinetics after intravenous and intramuscular administration.

Authors:  T B Tjandramaga; A Mullie; R Verbesselt; P J De Schepper; L Verbist
Journal:  Antimicrob Agents Chemother       Date:  1978-12       Impact factor: 5.191
  3 in total
  4 in total

1.  Single dose piperacillin in gonococcal urethritis.

Authors:  R G Masterton; N A Harrison
Journal:  Genitourin Med       Date:  1988-04

2.  Single dose piperacillin in treating uncomplicated gonococcal urethritis in men.

Authors:  T Thirumoorthy; K B Lim; C T Lee; E H Sng
Journal:  Genitourin Med       Date:  1987-10

3.  Comparison of piperacillin and penicillin in the treatment of uncomplicated gonorrhea.

Authors:  M L Simpson; M Y Khan; Y Siddiqui; R P Gruninger; D I Wigren
Journal:  Antimicrob Agents Chemother       Date:  1982-05       Impact factor: 5.191

Review 4.  Piperacillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  B Holmes; D M Richards; R N Brogden; R C Heel
Journal:  Drugs       Date:  1984-11       Impact factor: 9.546
  4 in total

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