| Literature DB >> 6458333 |
J P Rossi, P J Garrahan, A F Rega.
Abstract
(1) Vanadate (pentavalent vanadium) inhibits with high affinity (K0.5 = 3 microM) the ATP-dependent Ca2+ efflux in reconstituted ghosts from human red cell. (2) To inhibit Ca2+ efflux vanadate has to have access to the inner surface of the cell membrane (3) The inhibitory effect of vanadate is potentiated by intracellular Mg2+ and by intracellular K+. (4) Ca2+ in the external medium antagonizes the inhibitory effect of vanadate.Entities:
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Year: 1981 PMID: 6458333 DOI: 10.1016/0005-2736(81)90029-8
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002