Literature DB >> 6458237

Mezlocillin enteral absorption in rabbits.

K J Lavelle, M E Brier, G R Aronoff.   

Abstract

To determine the role of enterohepatic recirculation on its nonlinear elimination, we studied the enteral absorption of mezlocillin in rabbits. Mezlocillin was not substantially absorbed from the stomach or duodenum. We conclude that enterohepatic recirculation does not cause the dose-dependent elimination kinetics of mezlocillin.

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Year:  1981        PMID： 6458237      PMCID： PMC181713          DOI： 10.1128/AAC.20.3.418

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  3 in total

1.  Mezlocillin pharmacokinetics in renal impairment.

Authors:  G R Aronoff; R S Sloan; F C Luft; R L Nelson; D R Maxwell; S A Kleit
Journal:  Clin Pharmacol Ther       Date:  1980-10       Impact factor: 6.875

2.  Pharmacokinetics of mezlocillin in healthy volunteers.

Authors:  T Bergan
Journal:  Antimicrob Agents Chemother       Date:  1978-12       Impact factor: 5.191

3.  Mezlocillin pharmacokinetics in patients with normal and impaired renal functions.

Authors:  T Bergan; E K Brodwall; E Wiik-Larsen
Journal:  Antimicrob Agents Chemother       Date:  1979-11       Impact factor: 5.191
  3 in total
  1 in total

1.  Dose-dependent pharmacokinetics of mezlocillin in rats.

Authors:  G L Jungbluth; W J Jusko
Journal:  Antimicrob Agents Chemother       Date:  1989-06       Impact factor: 5.191
  1 in total

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