Literature DB >> 6456927

The effect of diphosphonates on periosteal and bone cells in culture.

R Felix, H Fleisch.   

Abstract

Calvaria cells were separated into periosteal and bone cells and cultured in the presence of ethane-1-hydroxy-1,1-diphosphonate (EHDP) or dichloromethanediphosphonate (Cl2MDP). Both cell types were affected to the same degree with respect to the effect on cell number and lactate production. The action of the diphosphonates seems therefore not to be specific for one of the cell types.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 6456927     DOI： 10.1007/bf01985657

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  21 in total

1.  Effects of 1-hydroxyethane-1,1-diphosphonate and dichloromethanediphosphonate on rabbit articular chondrocytes in culture.

Authors:  H L Guenther; H E Guenther; H Fleisch
Journal:  Biochem J       Date:  1979-11-15       Impact factor: 3.857

2.  Separation of parathyroid hormone and calcitonin-sensitive cells from non-responsive bone cells.

Authors:  G Wong; D V Cohn
Journal:  Nature       Date:  1974-12-20       Impact factor: 49.962

3.  The inhibitory effect of phosphonates on the formation of calcium phosphate crystals in vitro and on aortic and kidney calcification in vivo.

Authors:  H A Fleisch; R G Russell; S Bisaz; R C Mühlbauer; D A Williams
Journal:  Eur J Clin Invest       Date:  1970-03       Impact factor: 4.686

4.  Disodium etidronate in the prevention of heterotopic ossification following spinal cord injury (preliminary report).

Authors:  S L Stover; H R Hahn; J M Miller
Journal:  Paraplegia       Date:  1976-08

5.  Increase in alkaline phosphatase activity in calvaria cells cultured with diphosphonates.

Authors:  R Felix; H Fleisch
Journal:  Biochem J       Date:  1979-10-01       Impact factor: 3.857

6.  Effects of dichloromethylene diphosphonate on skeletal mobilization of calcium in multiple myeloma.

Authors:  E S Siris; W H Sherman; D C Baquiran; J P Schlatterer; E F Osserman; R E Canfield
Journal:  N Engl J Med       Date:  1980-02-07       Impact factor: 91.245

7.  Effect of diphosphonates on glycogen content of rabbit ear cartilage cells in culture.

Authors:  R Felix; D K Fast; J D Sallis; H Fleisch
Journal:  Calcif Tissue Int       Date:  1980       Impact factor: 4.333

8.  The comparative effects of dichloromethylene diphosphonate (C12MDP) and ethane-1-hydroxy-1,1-diphosphonate (EHDP) on growth and modeling of the rat tibia.

Authors:  S C Miller; W S Jee
Journal:  Calcif Tissue Res       Date:  1977-10-20

9.  Inhibition of osteolytic bone lesions by (3-amino-1-hydroxypropylidene)-1, 1-bisphosphonate (A.P.D.).

Authors:  F J van Breukelen; O L Bijvoet; A T van Oosterom
Journal:  Lancet       Date:  1979-04-14       Impact factor: 79.321

10.  Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates.

Authors:  R Felix; H Fleisch
Journal:  Biochem J       Date:  1981-04-15       Impact factor: 3.857
View more
  8 in total

1.  The procalcitonin amino-terminal cleavage peptide (N-proCT) lacks biological activity on normal clonal rat osteoblastic and preosteoblastic cells in vitro.

Authors:  H L Guenther; H Fleisch
Journal:  Calcif Tissue Int       Date:  1991-08       Impact factor: 4.333

2.  Effect of 1-hydroxyethylidene-1,1-bisphosphonate (HEBP) and dichloromethylidene-bisphosphonate (Cl2MBP) on the structure of the organic matrix of heterotopically induced bone tissue.

Authors:  K Ostrowski; A Wojtowicz; A Dziedzic-Goclawska; M Rozycka
Journal:  Histochemistry       Date:  1988

3.  Fatty acid oxidation in bone tissue and bone cells in culture. Characterization and hormonal influences.

Authors:  G Adamek; R Felix; H L Guenther; H Fleisch
Journal:  Biochem J       Date:  1987-11-15       Impact factor: 3.857

4.  Anticancer activity of bisphosphonic acids in methylnitrosourea-induced mammary carcinoma of the rat--benefit of combining bisphosphonates with cytostatic agents.

Authors:  F Wingen; B L Pool; P Klein; T Klenner; D Schmähl
Journal:  Invest New Drugs       Date:  1988-09       Impact factor: 3.850

5.  Comparative study of deflazacort, a new synthetic corticosteroid, and dexamethasone on the synthesis of collagen in different rat bone cell populations and rabbit articular chondrocytes.

Authors:  H L Guenther; R Felix; H Fleisch
Journal:  Calcif Tissue Int       Date:  1984-03       Impact factor: 4.333

6.  Synthesis, antitumor activity, distribution and toxicity of 4-[4-[bis(2-chloroethyl)amino]phenyl]-1-hydroxybutane-1 1-bisphosphonic acid (BAD), a new lost derivative with increased accumulation in rat osteosarcoma.

Authors:  F Wingen; H Sterz; H Blum; H Möller; W Pittermann; B L Pool; H J Sinn; H Spring; D Schmähl
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

7.  Differential response of bone cells isolated by sequential digestion to dichloromethylenebisphonate in culture.

Authors:  H L Guenther; J A Gallagher; H Fleisch
Journal:  Calcif Tissue Int       Date:  1984-09       Impact factor: 4.333

Review 8.  Clodronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease.

Authors:  G L Plosker; K L Goa
Journal:  Drugs       Date:  1994-06       Impact factor: 9.546
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.