Literature DB >> 6456926

The serum levels of unbound bilirubin that induce changes in some brain mitochondrial reactions in newborn guinea-pigs.

M A Almeida, L Rezende.   

Abstract

Bilirubin in different concentrations was injected in newborn guinea-pigs and the following parameters were determined: serum total and unbound bilirubin, whole brain bilirubin content and oxygen consumption, NADH-cytochrome c reductase and ATPase activities in brain mitochondria. The results showed a significant correlation between decreased rates of brain metabolism and the elevation of serum total and unbound bilirubin.

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Year:  1981        PMID： 6456926     DOI： 10.1007/bf01985651

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation.

Authors:  E G GRAY; V P WHITTAKER
Journal:  J Anat       Date:  1962-01       Impact factor: 2.610

2.  Bilirubin, an uncoupler of oxidative phosphorylation in isolated mitochondria.

Authors:  L ERNSTER; R ZETTERSTROM
Journal:  Nature       Date:  1956-12-15       Impact factor: 49.962

Review 3.  Biochemical alterations in neonatal hyperbilirubinemia and bilirubin encephalopathy: a review.

Authors:  W B Karp
Journal:  Pediatrics       Date:  1979-09       Impact factor: 7.124

4.  Determination of unbound bilirubin in the serum of newborns.

Authors:  J Jacobsen; R P Wennberg
Journal:  Clin Chem       Date:  1974-07       Impact factor: 8.327

5.  Mitochondrial abnormalities in bilirubin encephalopathy.

Authors:  H S Schutta; L Johnson; H E Neville
Journal:  J Neuropathol Exp Neurol       Date:  1970-04       Impact factor: 3.685

6.  Effects of bilirubin on mitochondrial reactions.

Authors:  M G Mustafa; M L Cowger; T E King
Journal:  J Biol Chem       Date:  1969-12-10       Impact factor: 5.157

7.  Estimation of unbound serum bilirubin by the peroxidase assay method: effect of exchange transfusion on unbound bilirubin and serum bindings.

Authors:  H D Arkans; G Cassady
Journal:  J Pediatr       Date:  1978-06       Impact factor: 4.406

8.  Improved micro-method for determination of serum bilirubin.

Authors:  R G Martinek
Journal:  Clin Chim Acta       Date:  1966-02       Impact factor: 3.786

9.  Experimental bilirubin encephalopathy. The mode of entry of bilirubin-14C into the central nervous system.

Authors:  I Diamond; R Schmid
Journal:  J Clin Invest       Date:  1966-05       Impact factor: 14.808

10.  Relationship between plasma unbound-bilirubin concentration and cerebellar bilirubin content in homozygous Gunn rat sucklings.

Authors:  H Sato; R Semba
Journal:  Experientia       Date:  1978-02-15
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