Literature DB >> 6455671

Fluorinated pyrimidines as tight-binding inhibitors of thymidylate synthetase.

P V Danenberg, A Lockshin.   

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Year:  1981        PMID： 6455671     DOI： 10.1016/0163-7258(81)90068-1

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


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  12 in total

1.  Effect of 5-fluoro-2'-deoxyuridine on [h]thymidine incorporation by bacterioplankton in the waters of southwest Florida.

Authors:  W H Jeffrey; J H Paul
Journal:  Appl Environ Microbiol       Date:  1988-02       Impact factor: 4.792

2.  Toxicity and effects of adjuvant therapy in colon cancer: results of the German prospective, controlled randomized multicenter trial FOGT-1.

Authors:  L Staib; K H Link; H G Beger
Journal:  J Gastrointest Surg       Date:  2001 May-Jun       Impact factor: 3.452

Review 3.  Chemotherapeutic implications in microsatellite unstable colorectal cancer.

Authors:  Won-Seok Jo; John M Carethers
Journal:  Cancer Biomark       Date:  2006       Impact factor: 4.388

4.  Mismatch repair proficiency and in vitro response to 5-fluorouracil.

Authors:  J M Carethers; D P Chauhan; D Fink; S Nebel; R S Bresalier; S B Howell; C R Boland
Journal:  Gastroenterology       Date:  1999-07       Impact factor: 22.682

5.  Prodrug activation by Cryptosporidium thymidine kinase.

Authors:  Xin E Sun; Lisa Sharling; Mani Muthalagi; Devaraja G Mudeppa; Krzysztof W Pankiewicz; Krzysztof Felczak; Pradipsinh K Rathod; Jan Mead; Boris Striepen; Lizbeth Hedstrom
Journal:  J Biol Chem       Date:  2010-03-15       Impact factor: 5.157

6.  Biological modification of protracted infusion of 5-fluorouracil with weekly leucovorin. A dose seeking clinical trial for patients with disseminated gastrointestinal cancers.

Authors:  C G Leichman; L Leichman; C P Spears; P J Rosen; F Muggia; S Jeffers; W Waugh
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

7.  Kinetics of Plasmodium falciparum thymidylate synthase: interactions with high-affinity metabolites of 5-fluoroorotate and D1694.

Authors:  M Hekmat-Nejad; P K Rathod
Journal:  Antimicrob Agents Chemother       Date:  1996-07       Impact factor: 5.191

Review 8.  Standing the test of time: targeting thymidylate biosynthesis in cancer therapy.

Authors:  Peter M Wilson; Peter V Danenberg; Patrick G Johnston; Heinz-Josef Lenz; Robert D Ladner
Journal:  Nat Rev Clin Oncol       Date:  2014-04-15       Impact factor: 66.675

9.  Molecular targets of 5-fluoroorotate in the human malaria parasite, Plasmodium falciparum.

Authors:  P K Rathod; N P Leffers; R D Young
Journal:  Antimicrob Agents Chemother       Date:  1992-04       Impact factor: 5.191

Review 10.  Clinical pharmacology of 5-fluorouracil.

Authors:  R B Diasio; B E Harris
Journal:  Clin Pharmacokinet       Date:  1989-04       Impact factor: 6.447
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