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Literature DB >> 6455328

The detection of mutants in mice by electrophoresis: results of a model induction experiment with procarbazine.

F M Johnson, G T Roberts, R K Sharma, F Chasalow, R Zweidinger, A Morgan, R W Hendren, S E Lewis.

Abstract

Male mice of the DBA/2J strain were treated with the mutagen procarbazine and mated with C57BL/6J females. Offspring and parents were then analyzed for electrophoretically expressed mutations. A control group, not mutagen treated, was also examined. Two mutants probably due to induction were identified, and several of spontaneous origin were also found.

Entities: Chemical Species

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Year: 1981 PMID： 6455328 PMCID： PMC1214378

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

14 in total

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Authors: R A Voelker; C H Langley; A J Brown; S Ohnishi; B Dickson; E Montgomery; S C Smith
Journal: Proc Natl Acad Sci U S A Date: 1980-02 Impact factor: 11.205

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Authors: G Schlager; M M Dickie
Journal: Genetics Date: 1967-10 Impact factor: 4.562

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Authors: A J Katz
Journal: Mutat Res Date: 1978-06 Impact factor: 2.433

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Authors: H V Malling; L R Valcovic
Journal: Arch Toxicol Date: 1977-09-21 Impact factor: 5.153

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Authors: T H Roderick; F H Ruddle; V M Chapman; T B Shows
Journal: Biochem Genet Date: 1971-10 Impact factor: 1.890

7. Drosophila melanogaster: Inheritance of a Deficiency of Alkaline Phosphatase in Larvae.

Authors: F M Johnson
Journal: Science Date: 1966-04-15 Impact factor: 47.728

8. Action of N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide hydrochloride (procarbazine hydrochloride) in the germ tissue of mice: dominant lethal effects.

Authors: G T Roberts; F M Johnson; H V Malling; R K Sharma
Journal: Arch Toxicol Date: 1979-02-23 Impact factor: 5.153

9. Hemoglobin Beta chain structural variation in mice: evolutionary and functional implications.

Authors: J G Gilman
Journal: Science Date: 1972-11-24 Impact factor: 47.728

10. An approach to measuring germinal mutations in the mouse.

Authors: L R Valcovic; H V Malling
Journal: Environ Health Perspect Date: 1973-12 Impact factor: 9.031

8 in total

Review 1. Subline divergence within L.C. Strong's C3H and CBA inbred mouse strains. A review.

Authors: A C Whitmore; S P Whitmore
Journal: Immunogenetics Date: 1985 Impact factor: 2.846

2. The rate with which spontaneous mutation alters the electrophoretic mobility of polypeptides.

Authors: J V Neel; C Satoh; K Goriki; M Fujita; N Takahashi; J Asakawa; R Hazama
Journal: Proc Natl Acad Sci U S A Date: 1986-01 Impact factor: 11.205

3. The occurrence of a regulatory mutation in postirradiation offspring of convict cichlid fish, Cichlasoma nigrofasciatum (Pisces, Perciformes).

Authors: C J Wu; J H Schröder
Journal: Biochem Genet Date: 1983-12 Impact factor: 1.890