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Literature DB >> 6455096

Bronchodilator effects of clemastine, ipratropium, bromide, and salbutamol in preschool children with asthma.

Abstract

The bronchodilator activity in nebulised salbutamol, ipratropium bromide, clemastine, and a placebo was studied in 14 asthmatic children aged between 3 and 5 years. Changes in lung function were monitored by measuring peak expiratory flow rate and total respiratory resistance using a modification of the forced oscillation technique. Ipratropium bromide produced a degree of bronchodilation similar to that of salbutamol, but the bronchodilatory activity of clemastine was not appreciably better than for the placebo.

Entities: Chemical Disease Species

Mesh：

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Year: 1981 PMID： 6455096 PMCID： PMC1627441 DOI： 10.1136/adc.56.5.342

Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791

13 in total

1. Forced oscillation technique for determination of resistance to breathing in children.

Authors: J J Cogswell
Journal: Arch Dis Child Date: 1973-04 Impact factor: 3.791

2. Peak expiratory flow rates in children under 5 years of age.

Authors: A D Milner; D Ingram
Journal: Arch Dis Child Date: 1970-12 Impact factor: 3.791

3. Distribution of bronchodilatation in normal subjects: beta agonist versus atropine.

Authors: M J Hensley; C F O'Cain; E R McFadden; R H Ingram
Journal: J Appl Physiol Respir Environ Exerc Physiol Date: 1978-11

4. Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. II.

Authors: J M Tanner; R H Whitehouse; M Takaishi
Journal: Arch Dis Child Date: 1966-12 Impact factor: 3.791

5. A comparative study of atropine methonitrate, salbutamol, and their combination in airways obstruction.

Authors: R J Pierce; C J Allen; A H Campbell
Journal: Thorax Date: 1979-02 Impact factor: 9.139

6. Bronchodilatation after inhalation of the antihistamine clemastine.

Authors: S G Nogrady; J P Hartley; P D Handslip; N P Hurst
Journal: Thorax Date: 1978-08 Impact factor: 9.139

7. A clinical trial of the bronchodilator effect of Sch 1000 aerosol in asthmatic children.

Authors: M T Lin; E Lee-Hong; C Collins-Williams
Journal: Ann Allergy Date: 1978-05

8. Sodium cromoglycate and ipratropium bromide in exercise-induced asthma.

Authors: N C Thomson; K R Patel; J W Kerr
Journal: Thorax Date: 1978-12 Impact factor: 9.139

9. Recurrent wheezing in the preschool child.

Authors: W Lenney; A D Milner
Journal: Arch Dis Child Date: 1978-06 Impact factor: 3.791

10. At what age do bronchodilator drugs work?

Authors: W Lenney; A D Milner
Journal: Arch Dis Child Date: 1978-07 Impact factor: 3.791

11 in total

1. Abnormalities of lung mechanics in young asthmatic children.

Authors: A Greenough; B G Loftus; J Pool; J F Price
Journal: Thorax Date: 1987-07 Impact factor: 9.139

2. Nebulised ipratropium and salbutamol in asthma.

Authors: J Storr; W Lenney
Journal: Arch Dis Child Date: 1986-06 Impact factor: 3.791

3. Response to bronchodilators assessed by lung mechanics.

Authors: A Greenough; B G Loftus; J Pool; J F Price
Journal: Arch Dis Child Date: 1986-10 Impact factor: 3.791

Review 4. Asthma: 2. Trends in pharmacologic therapy.

Authors: A S Rebuck; K R Chapman
Journal: CMAJ Date: 1987-03-01 Impact factor: 8.262

Review 5. Acute airways obstruction in children under 5.

Authors: A D Milner; R L Henry
Journal: Thorax Date: 1982-09 Impact factor: 9.139

6. Bronchodilator effect of inhaled ipratropium bromide in wheezy toddlers.

Authors: I G Hodges; R C Groggins; A D Milner; G M Stokes
Journal: Arch Dis Child Date: 1981-09 Impact factor: 3.791

7. Response to bronchodilator drugs in the first years of life.

Authors: A D Milner
Journal: Eur J Clin Pharmacol Date: 1980-07 Impact factor: 2.953

Review 8. The role of anticholinergic antimuscarinic bronchodilator therapy in children.

Authors: M Silverman
Journal: Lung Date: 1990 Impact factor: 2.584

9. Nebulised therapy in acute severe bronchiolitis in infancy.

Authors: G M Stokes; A D Milner; I G Hodges; R L Henry; M C Elphick
Journal: Arch Dis Child Date: 1983-04 Impact factor: 3.791

10. Salbutamol and ipratropium in acute asthma.

Authors: R J Rayner; P H Cartlidge; C J Upton
Journal: Arch Dis Child Date: 1987-08 Impact factor: 3.791