Literature DB >> 6454134

'In situ' immune complex nephritis and basic proteins.

A Vogt, H U Schmidt, H Takamiya, S Batsford.   

Abstract

This investigation was designed to clarify the potential role of basic antigens in immune complex nephritis. The GBM is negatively charged and binds cationic substances. We studied 1) whether chemically cationised proteins can bind to the GBM, act as planted antigen, and induce 'in situ' immune complex formation or 2) if a pre-formed cationic antigen antibody complex can localise in the GBM. Results obtained with 5 chemically cationised proteins support the first possibility.

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Year:  1980        PMID： 6454134

Source DB:  PubMed          Journal:  Proc Eur Dial Transplant Assoc        ISSN： 0071-2736


  9 in total

1.  [A new concept for the pathogenesis of immune complex nephritis].

Authors:  A Vogt; S R Batsford
Journal:  Klin Wochenschr       Date:  1982-09-15

2.  Staphylococcal acid phosphatase binds to endothelial cells via charge interaction; a pathogenic role in Wegener's granulomatosis?

Authors:  R H Brons; H I Bakker; R T Van Wijk; N W Van Dijk; A C Muller Kobold; P C Limburg; W L Manson; C G Kallenberg; J W Tervaert
Journal:  Clin Exp Immunol       Date:  2000-03       Impact factor: 4.330

3.  Streptococcus mutans-induced nephritis in rabbits.

Authors:  B Albini; R J Nisengard; I Glurich; M E Neiders; M W Stinson
Journal:  Am J Pathol       Date:  1985-03       Impact factor: 4.307

4.  Preservation of fixed anionic sites in the GBM in the acute proteinuric phase of cationic antigen mediated in-situ immune complex glomerulonephritis in the rat.

Authors:  Y Suzuki; Y Maruyama; M Arakawa; T Oite
Journal:  Histochemistry       Date:  1984

5.  Isolation and characterization of inflammatory leukocytes from glomeruli in an in situ model of glomerulonephritis in the rat.

Authors:  H T Cook; J Smith; V Cattell
Journal:  Am J Pathol       Date:  1987-01       Impact factor: 4.307

6.  An active model of immune complex glomerulonephritis in the rat employing cationized antigen.

Authors:  T Oite; F Shimizu; I Kihara; S R Batsford; A Vogt
Journal:  Am J Pathol       Date:  1983-08       Impact factor: 4.307

7.  Surface charge distribution is a determinant of antigen deposition in the renal glomerulus: studies employing 'charge-hybrid' molecules.

Authors:  S R Batsford; M J Mihatsch; M Rawiel; T M Schmiedeke; A Vogt
Journal:  Clin Exp Immunol       Date:  1991-12       Impact factor: 4.330

8.  The effect of protamine sulfate on the course of immune complex glomerulonephritis in the rat.

Authors:  T Oite; F Shimizu; S R Batsford; A Vogt
Journal:  Clin Exp Immunol       Date:  1986-05       Impact factor: 4.330

9.  Quantitative studies of in situ immune complex glomerulonephritis in the rat induced by planted, cationized antigen.

Authors:  T Oite; S R Batsford; M J Mihatsch; H Takamiya; A Vogt
Journal:  J Exp Med       Date:  1982-02-01       Impact factor: 14.307
  9 in total

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