Literature DB >> 6452281

Interleukin 2, production in the syngeneic mixed lymphocyte reaction.

E C Lattime, S Gillis, C David, O Stutman.   

Abstract

In the syngeneic mixed lymphocyte reaction, Ly 1 cells proliferate following stimulation with Ia-positive macrophage-like cells. The proliferation is accompanied by the release of interleukin 2 into the medium. Both the proliferation and interleukin 2 production are dependent on the expression of Ia antigenic determinants, as the addition of haplotype-specific anti-Ia antisera to the cultures inhibits both parameters.

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Year:  1981        PMID: 6452281     DOI: 10.1002/eji.1830110115

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN: 0014-2980            Impact factor:   5.532


  10 in total

1.  Impaired autologous mixed lymphocyte reaction (AMLR) reactivity of peripheral blood T cell subsets in rheumatoid arthritis.

Authors:  E C Keystone; L Poplonski; K M Snow; M Martell
Journal:  Clin Exp Immunol       Date:  1989-11       Impact factor: 4.330

2.  Intimate host-tumor interaction in the spontaneous reticulum cell sarcoma of SJL/J mice: is it an exceptional case?

Authors:  B Bonavida
Journal:  Surv Immunol Res       Date:  1985

3.  Frequency in human peripheral blood of T cells which respond to self, modified self and alloantigens.

Authors:  J B Smith
Journal:  Immunology       Date:  1983-10       Impact factor: 7.397

4.  Antigen presentation to human T lymphocytes. I. Different requirements for stimulation by hapten-modified cells vs. cell sonicates.

Authors:  S L Abramson; J M Puck; R R Rich
Journal:  J Exp Med       Date:  1981-10-01       Impact factor: 14.307

5.  Defective LN cell proliferative response to Sm antigen in mice bearing the lpr gene.

Authors:  H Dang; M Fischbach; V Fey; N Talal
Journal:  Clin Exp Immunol       Date:  1984-05       Impact factor: 4.330

6.  T-suppressor clones derived from murine AMLR.

Authors:  M H Bocchieri
Journal:  Immunology       Date:  1985-09       Impact factor: 7.397

7.  Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism.

Authors:  K Inaba; A Granelli-Piperno; R M Steinman
Journal:  J Exp Med       Date:  1983-12-01       Impact factor: 14.307

8.  Production of a cytokine with interleukin 3-like properties and cytokine-dependent proliferation in human autologous mixed lymphocyte reaction.

Authors:  R Suzuki; S Suzuki; T Takahashi; K Kumagai
Journal:  J Exp Med       Date:  1986-11-01       Impact factor: 14.307

9.  Helper cells in the autologous mixed lymphocyte reaction. III. Production of helper factor(s) distinct from interleukin 2.

Authors:  J A Wolos; J B Smith
Journal:  J Exp Med       Date:  1982-12-01       Impact factor: 14.307

10.  Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene.

Authors:  D Wofsy; E D Murphy; J B Roths; M J Dauphinée; S B Kipper; N Talal
Journal:  J Exp Med       Date:  1981-11-01       Impact factor: 14.307

  10 in total

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