Literature DB >> 6451449

Mast cell stabilizing compound FPL 55618 reduces right ventricular hypertrophy and lung mast cell hyperplasia in chronically hypoxic rats.

J M Kay, K L Suyama, P M Keane.   

Abstract

Rats treated with chronic hypobaric hypoxia (21 days, 380 Torr) and mast cell stabilizing compound FPL 55618 had significantly less right ventricular hypertrophy and lung mast cell hyperplasia than rats subjected to chronic hypoxia alone. Right ventricular blood pressure was not reduced.

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Year:  1981        PMID: 6451449     DOI: 10.1007/bf01965579

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  H1 and H2 histamine actions on lung vessels; their relevance to hypoxic vasoconstriction.

Authors:  G R Barer; C J Emery; F H Mohammed; I P Mungall
Journal:  Q J Exp Physiol Cogn Med Sci       Date:  1978-04

2.  Lung mast cells in rats exposed to acute hypoxia, and chronic hypoxia with recovery.

Authors:  A Williams; D Heath; J M Kay; P Smith
Journal:  Thorax       Date:  1977-06       Impact factor: 9.139

3.  A simplified toluidine blue stain for mast cells.

Authors:  E Schueller; M Peutsch; L G Bohacek; R K Gupta
Journal:  Can J Med Technol       Date:  1967-08

Review 4.  Disodium cromoglycate. Mode of action and its possible relevance to the clinical use of the drug.

Authors:  J S Cox
Journal:  Br J Dis Chest       Date:  1971-10

Review 5.  Humoral control of the pulmonary circulation.

Authors:  E H Bergofsky
Journal:  Annu Rev Physiol       Date:  1980       Impact factor: 19.318

6.  Effect of intermittent normoxia on chronic hypoxic pulmonary hypertension, right ventricular hypertrophy, and polycythemia in rats.

Authors:  J M Kay
Journal:  Am Rev Respir Dis       Date:  1980-06

Review 7.  Disodium cromoglycate (Intal).

Authors:  J S Cox; J E Beach; A M Blair; A J Clarke; J King; T B Lee; D E Loveday; G F Moss; T S Orr; J T Ritchie; P Sheard
Journal:  Adv Drug Res       Date:  1970

8.  Role of the mast cell in the pulmonary pressor response to hypoxia.

Authors:  F Haas; E H Bergofsky
Journal:  J Clin Invest       Date:  1972-12       Impact factor: 14.808

9.  Lung mast cell density and distribution in chronically hypoxic animals.

Authors:  A Tucker; I F McMurtry; A F Alexander; J T Reeves; R F Grover
Journal:  J Appl Physiol Respir Environ Exerc Physiol       Date:  1977-02

10.  Hypoxia and lung mast cells: influence of disodium cromoglycate.

Authors:  I P Mungall
Journal:  Thorax       Date:  1976-02       Impact factor: 9.139

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  2 in total

1.  Acute and chronic hypoxia as well as 7-day recovery from chronic hypoxia affects the distribution of pulmonary mast cells and their MMP-13 expression in rats.

Authors:  Ludek Vajner; Richard Vytásek; Vera Lachmanová; Jirí Uhlík; Václava Konrádová; Jana Novotná; Václav Hampl; Jan Herget
Journal:  Int J Exp Pathol       Date:  2006-10       Impact factor: 1.925

Review 2.  Inflammation in Right Ventricular Failure: Does It Matter?

Authors:  Laurence Dewachter; Céline Dewachter
Journal:  Front Physiol       Date:  2018-08-20       Impact factor: 4.566

  2 in total

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