Literature DB >> 6451338

Immune regulation in inflammatory bowel disease: absence of a serum inhibitor of suppressor cell function.

B J Kemler, E Alpert.   

Abstract

Suppressor cell function of normal peripheral blood mononuclear cells was unaltered by preincubation with sera from patients with severe inflammatory bowel disease (IBD). These results suggest that, in contrast to juvenile rheumatoid arthritis and systemic lupus erythematosus, the decreased suppressor cell activity in IBD is not mediated by anti-suppressor cell antibodies.

Entities:  

Mesh:

Year:  1980        PMID: 6451338      PMCID: PMC1537097     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN: 0009-9104            Impact factor:   4.330


  17 in total

1.  Suppressor T-cell abnormality in idiopathic systemic lupus erythematosus.

Authors:  N I Abdou; A Sagawa; E Pascual; J Hebert; S Sadeghee
Journal:  Clin Immunol Immunopathol       Date:  1976-09

2.  Decreased suppressor cell activity in inflammatory bowel disease.

Authors:  H J Hodgson; J R Wands; K J Isselbacher
Journal:  Clin Exp Immunol       Date:  1978-06       Impact factor: 4.330

3.  Serum lymphocytotoxic and lymphocytophilic antibody activity in inflammatory bowel disease.

Authors:  S Korsmeyer; R G Strickland; I D Wilson; R C Williams
Journal:  Gastroenterology       Date:  1974-10       Impact factor: 22.682

4.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

5.  Further studies on in vitro cytotoxicity of lymphocytes from patients with ulcerative and granulomatous colitis for allogeneic colonic epithelial cells, including the effects of colectomy.

Authors:  R G Shorter; M Cardoza; R J Spencer; K A Huizenga
Journal:  Gastroenterology       Date:  1969-02       Impact factor: 22.682

6.  A serum inhibitor of immune regulation in patients with systemic lupus erythematosus.

Authors:  J J Twomey; A H Laughter; A D Steinberg
Journal:  J Clin Invest       Date:  1978-09       Impact factor: 14.808

7.  The distribution and enteric loss of 51Cr-labelled lymphocytes in normal subjects and in patients with coeliac disease and other disorders of the small intestine.

Authors:  A P Douglas; A P Weetman; J W Haggith
Journal:  Digestion       Date:  1976       Impact factor: 3.216

8.  Suppressor function of peripheral blood mononuclear cells in normal individuals and in patients with systemic lupus erythematosus.

Authors:  B Bresnihan; H E Jasin
Journal:  J Clin Invest       Date:  1977-01       Impact factor: 14.808

9.  Short-term course and prognosis of Crohn's disease.

Authors:  F T De Dombal; I L Burton; S E Clamp; J C Goligher
Journal:  Gut       Date:  1974-06       Impact factor: 23.059

10.  Suppressor cell activity after concanavalin A treatment of lymphocytes from normal donors.

Authors:  L Shou; S A Schwartz; R A Good
Journal:  J Exp Med       Date:  1976-05-01       Impact factor: 14.307

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