Literature DB >> 6450728

Characterization of rat spleen cell populations. II. Activation by antigens and allogeneic cells.

B Rocha, A A Freitas, D Parrott.   

Abstract

Spleen cells from BN rats were separated in a discontinuous density gradient. Cells from different fractions were shown to be functionally diverse. Light cells were highly responsive in MLR, generated little killer activity and enhanced syngeneic recipient's IgM and IgG production in response to SRBC. Dense cells were unable to respond in MLR and suppress Ab response. Maximum killer activity was recovered from medium density fractions which were probably mixtures of helper and suppressor cells.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6450728      PMCID： PMC1458312     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  17 in total

1.  Fractionation of lymphocyte subpopulations which regulate mixed lymphocyte reactions.

Authors:  R R Rich; L Chu; S S Rich
Journal:  J Immunol       Date:  1977-04       Impact factor: 5.422

2.  Size distribution of in-vitro-induced antigen-specific helper and suppressor cells.

Authors:  L C Andersson; P Häyry; S Kontiainen
Journal:  Scand J Immunol       Date:  1977       Impact factor: 3.487

3.  A rapid method for the isolation of functional thymus-derived murine lymphocytes.

Authors:  M H Julius; E Simpson; L A Herzenberg
Journal:  Eur J Immunol       Date:  1973-10       Impact factor: 5.532

4.  "Spontaneous" B cell activation due to loss of normal mouse serum suppressor.

Authors:  W W Bullock; E Möller
Journal:  Eur J Immunol       Date:  1972-12       Impact factor: 5.532

5.  Cell-mediated cell lysis in vitro: genetic control of killer cell production and target specificities in the mouse.

Authors:  M Nabholz; J Vives; H M Young; T Meo; V Miggiano; A Rijnbeek; D C Shreffler
Journal:  Eur J Immunol       Date:  1974-05       Impact factor: 5.532

6.  Separation of stages in the development of the "T" cells involved in cell-mediated immunity.

Authors:  K Shortman; K T Brunner; J C Cerottini
Journal:  J Exp Med       Date:  1972-06-01       Impact factor: 14.307

7.  The selective elimination of immunologically competent cells from bone marrow and lymphocyte cell mixtures. 3. In vitro test for detection of immunocompetent cells in fractionated mouse spleen cell suspensions and primate bone marrow suspensions.

Authors:  K A Dicke; G Tridente; D W van Bekkum
Journal:  Transplantation       Date:  1969-10       Impact factor: 4.939

8.  Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.

Authors:  H Cantor; E A Boyse
Journal:  J Exp Med       Date:  1975-06-01       Impact factor: 14.307

9.  Separation of helper T cells from suppressor T cells expressing different Ly components. I. Polyclonal activation: suppressor and helper activities are inherent properties of distinct T-cell subclasses.

Authors:  J Jandinski; H Cantor; T Tadakuma; D L Peavy; C W Pierce
Journal:  J Exp Med       Date:  1976-06-01       Impact factor: 14.307

10.  Heterogeneity of murine regulatory T cells. I. Subpopulations of amplifier and suppressor T cells.

Authors:  R L Whisler; J D Stobo
Journal:  J Exp Med       Date:  1976-08-01       Impact factor: 14.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.