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Literature DB >> 6448616

Glycosaminoglycan content and synthesis in gastric carcinoma.

M Sobue, J Takeuchi, K Miura, K Kawase, F Mizuno, E Sato.

Abstract

The glycosaminoglycan (GAG) content of stomach carcinoma tissue was compared with that of non-neoplastic mucosa. GAG synthesis was also studied, by an analysis of 35S-labelled material after incubation of tissue segments in medium containing 35SO4. No significant difference was found between the amount of GAG and its components in the medullary carcinoma tissue and in non-neoplastic mucosa, but GAG synthesis of the carcinoma tissue was at a much higher rate than that of the non-neoplastic mucosa. In the autoradiograph, high 35S uptake in the carcinoma cells was observed. The GAG content of the scirrhous-carcinoma tissue was about twice that of medullary carcinoma.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1980 PMID： 6448616 PMCID： PMC2010460 DOI： 10.1038/bjc.1980.205

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

27 in total

1. Glycosaminoglycans and electrokinetic behavior of rat ascites hepatoma cells.

Authors: K Kojima; T Yamagata
Journal: Exp Cell Res Date: 1971-07 Impact factor: 3.905

2. Studies of carcinogenesis by avian sarcoma viruses. II. Virus-induced increase in hyaluronic acid synthetase in chicken fibroblasts.

Authors: N Ishimoto; H M Temin; J L Strominger
Journal: J Biol Chem Date: 1966-05-10 Impact factor: 5.157

Review 5. The dual role of the glycosaminoglycan chondroitin-6-sulfate in the development, progression and metastasis of cancer.

Authors: Adam Pudełko; Grzegorz Wisowski; Krystyna Olczyk; Ewa Maria Koźma
Journal: FEBS J Date: 2019-02-05 Impact factor: 5.542

5 in total

Glycosaminoglycan content and synthesis in gastric carcinoma.

1. Glycosaminoglycans and electrokinetic behavior of rat ascites hepatoma cells.

2. Studies of carcinogenesis by avian sarcoma viruses. II. Virus-induced increase in hyaluronic acid synthetase in chicken fibroblasts.

3. Production of sulfated mucopolysaccharides by established cell lines of fibroblastic and nonfibroblastic origin.

4. Immunohistological studies on gastric mucosal glycoprotein in gastric carcinoma.

5. Purification and properties of bacterial chondroitinases and chondrosulfatases.

6. Novel hyaluronidase from streptomyces.

7. Growth-promoting effect of acid mucopolysaccharides on Ehrlich ascites tumor.

8. Growth-promoting effect of chondroitin sulphate on solid Ehrlich ascites tumour.

9. Production of mucopolysaccharides by normal and transformed cells.

10. Acid mucopolysaccharide (glycosaminoglycan) at the epithelial-mesenchymal interface of mouse embryo salivary glands.

1. Immunohistochemical localization of proteoglycans in interstitial elements of human pancreas and biliary system.

2. Hyaluronan distribution in the normal epithelium of esophagus, stomach, and colon and their cancers.

3. Immunohistochemical localization of chondroitin sulphate and dermatan sulphate proteoglycans in tumour tissues.

4. Glycosaminoglycan-synthetic activity of neoplastic and non-neoplastic adipose tissues.

Review 5. The dual role of the glycosaminoglycan chondroitin-6-sulfate in the development, progression and metastasis of cancer.