| Literature DB >> 6448165 |
Abstract
Potentiation of the effect of haloperidol on dopamine metabolism by the 5-HT uptake inhibitor CGP 6085 A, and antagonism of this effect by the 5-HT antagonist mianserin were observed in the mesolimbic area and the frontal cortex of the rat brain. A similar effect was reported earlier in the corpus striatum. This suggests that serotoninergic modulation of dopamine neurons is a generally-occurring phenomenon in the brain.Entities:
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Year: 1980 PMID: 6448165 DOI: 10.1007/bf01965988
Source DB: PubMed Journal: Experientia ISSN: 0014-4754