Literature DB >> 6447658

Effect of streptozotocin diabetes on sialic acid content and glycoprotein binding of isolated hepatocytes.

G Durand, J P Dumont, M Appel, D Durand, J Davy, J Féger, J Agneray.   

Abstract

The possible correlation between sialic acid content of hepatocyte plasma membranes, and their binding capacity was investigated. For that purpose, [3H] asialotransferrin binding was tested with hepatocytes from both normal and streptozotocin treated rats. The observed decrease in binding capacity was parallel to a decrease in the sialic acid content Insulin therapy restored simultaneously normal blood glucose level, hepatic membrane sialic acid content and binding capacity.

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Year:  1980        PMID: 6447658     DOI: 10.1055/s-2007-996259

Source DB:  PubMed          Journal:  Horm Metab Res        ISSN: 0018-5043            Impact factor:   2.936


  4 in total

1.  In vivo quantification of removal of asialo-orosomucoid from the circulation in anaesthetized streptozotocin-diabetic rats.

Authors:  M Appel; P Potrat; J Feger; C Mas-Chamberlin; G Durand
Journal:  Diabetologia       Date:  1986-06       Impact factor: 10.122

2.  Total and ganglioside-bound sialic acid content of lymphocytes from non-insulin-dependent diabetic patients.

Authors:  M Gavella; V Lipovac; S Crnek
Journal:  Acta Diabetol Lat       Date:  1990 Oct-Dec

3.  Diabetic pregnancy. Changes in lectin binding to the surface of rat lung alveolar epithelial cells.

Authors:  M T Dixon; R A Jersild
Journal:  Am J Pathol       Date:  1983-12       Impact factor: 4.307

4.  Enhanced susceptibility of mice with streptozotocin-induced diabetes to type II group B streptococcal infection.

Authors:  M S Edwards; P A Fuselier
Journal:  Infect Immun       Date:  1983-02       Impact factor: 3.441

  4 in total

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