Literature DB >> 6447254

Surface activation of blood coagulation, fibrinolysis and kinin formation.

R L Heimark, K Kurachi, K Fujikawa, E W Davie.   

Abstract

The activation of plasma prekallikrein by single-chain factor XII has been studied in the presence of high molecular weight kininogen and kaolin. The data indicate that factor XII can initiate blood coagulation, fibrinolysis or kinin generation in the presence of kaolin and does so by converting prekallikrein to kallikrein. An enzyme cascade is then generated leading to the formation of fibrin, plasmin or bradykinin in three closely related physiological events.

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Year:  1980        PMID： 6447254     DOI： 10.1038/286456a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  9 in total

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2.  A frequent factor XII gene mutation in Hageman trait.

Authors:  F Bernardi; G Marchetti; S Volinia; P Patracchini; A Casonato; A Girolami; F Conconi
Journal:  Hum Genet       Date:  1988-10       Impact factor: 4.132

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4.  Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma.

Authors:  H Saito; S J Scialla
Journal:  J Clin Invest       Date:  1981-10       Impact factor: 14.808

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Review 8.  Serpins in thrombosis, hemostasis and fibrinolysis.

Authors:  J C Rau; L M Beaulieu; J A Huntington; F C Church
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9.  Inhibition of cell adhesion by high molecular weight kininogen.

Authors:  S Asakura; R W Hurley; K Skorstengaard; I Ohkubo; D F Mosher
Journal:  J Cell Biol       Date:  1992-01       Impact factor: 10.539
  9 in total

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