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Literature DB >> 6446879

Cefoperazone (T-1551), a new semisynthetic cephalosporin: comparison with cephalothin and gentamicin.

R N Jones, P C Fuchs, A L Barry, T L Gavan, H M Sommers, E H Gerlach.

Abstract

The in vitro activity of cefoperazone (T-1551) against almost 9,000 recent clinical isolates at six institutions was tested and compared with that of cephalothin and gentamicin. The modal minimum inhibitory concentrations of cefoperazone were 16- and 4-fold less than those of cephalothin and gentamicin, respectively, against 5,503 strains of Enterobacteriaceae. Species normally resistant to cephalothin, such as indole-positive protease and enterobacters, were almost universally susceptible to cefoperazone. Cefoperazone demonstrated activity comparable to gentamicin against Pseudomonas aeruginosa and other pseudomonads.

Entities: Chemical Species

Mesh：

Substances：

Year: 1980 PMID： 6446879 PMCID： PMC283865 DOI： 10.1128/AAC.17.4.743

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

15 in total

1. beta-lactamase stability of HR 756, a novel cephalosporin, compared to that of cefuroxime and cefoxitin.

Authors: K P Fu; H C Neu
Journal: Antimicrob Agents Chemother Date: 1978-09 Impact factor: 5.191

2. Cefuroxime, an in vitro Comparison with Six Other Cephalosporins.

Authors: A L Barry; C Thornsberry; R N Jones; P C Fuchs; T L Gavan; E H Gerlach
Journal: Proc R Soc Med Date: 1977

3. BL-S786, a new parenteral cephalosporin. II. In vitro antimicrobial activity comparison with six related cephalosporins.

Authors: R N Jones; C Thornsberry; A L Barry; P C Fuchs; T L Gavin; E H Gerlach
Journal: J Antibiot (Tokyo) Date: 1977-07 Impact factor: 2.649

4. BL-S786, a new parenteral cephalosporin. I. A collaborative in vitro susceptibility comparison to cephalothin against 5,762 clinical bacterial isolates.

Authors: R N Jones; P C Fuchs; T L Gavan; E H Gerlach; A Barry; C Thornsberry
Journal: J Antibiot (Tokyo) Date: 1977-07 Impact factor: 2.649

5. Cefuroxime, a new parenteral cephalosporin: collaborative in vitro susceptibility comparison with cephalothin against 5,887 clinical bacterial isolates.

Authors: R N Jones; P C Fuchs; T L Gavan; E H Gerlach; A L Barry; C Thornsberry
Journal: Antimicrob Agents Chemother Date: 1977-07 Impact factor: 5.191

6. Antibiotic sensitivity testing. Report of an international collaborative study.

Authors: H M Ericsson; J C Sherris
Journal: Acta Pathol Microbiol Scand B Microbiol Immunol Date: 1971

7. Comparative in vitro activity of newer cephalosporins against anaerobic bacteria.

Authors: A W Chow; D Bednorz
Journal: Antimicrob Agents Chemother Date: 1978-11 Impact factor: 5.191

8. Piperacillin (T-1220), a new semisynthetic penicillin: in vitro antimicrobial activity comparison with carbenicillin, ticarcillin, ampicillin, cephalothin, cefamandole and cefoxitin.

Authors: R N Jones; C Thornsberry; A L Barry; P C Fuchs; T L Gavan; E H Gerlach
Journal: J Antibiot (Tokyo) Date: 1977-12 Impact factor: 2.649

9. SCE-963, a new broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities.

Authors: K Tsuchiya; M Kida; M Kondo; H Ono; M Takeuchi; T Nishi
Journal: Antimicrob Agents Chemother Date: 1978-10 Impact factor: 5.191

10. Ticarcillin: a collaborative in vitro comparison with carbenicillin against over 9,000 clinical bacterial isolates.

Authors: P C Fuchs; T L Gavan; E H Gerlach; R N Jones; A L Barry; C Thornsberry
Journal: Am J Med Sci Date: 1977 Nov-Dec Impact factor: 2.378

29 in total

Review 1. Bacterial antibiotic resistance before and after clinical application in the United States.

Authors: A L Barry; R N Jones
Journal: Bull N Y Acad Med Date: 1987-04

2. Establishment of minimum inhibitory concentrations of cefoperazone for control and reference anaerobic organisms.

Authors: R J Zabransky; E Randall; V L Sutter; R J Birk; G Westenfelder; J Emmerman; A T Ghoneim
Journal: J Clin Microbiol Date: 1983-04 Impact factor: 5.948

3. Effect of temperature on antimicrobial susceptibilities of Pseudomonas maltophilia.

Authors: P F Wheat; T G Winstanley; R C Spencer
Journal: J Clin Pathol Date: 1985-09 Impact factor: 3.411

4. A clinical trial with cefoperazone in pneumonia and pyelonephritis.

Authors: S C Park; J H Lee; D H Lee; S Y Kim; Y H Kim; C H Park; S E Seok; Y K Lee; B C Chung; E S Sohn
Journal: Drugs Date: 1981 Impact factor: 9.546

5. Factors affecting the in vitro activity of cefoperazone against the Bacteroides fragilis group.

Authors: V L Sutter; Y Y Kwok
Journal: Antimicrob Agents Chemother Date: 1981-12 Impact factor: 5.191

6. Antimicrobial activity of amikacin combinations against Enterobacteriaceae moderately susceptible to third-generation cephalosporins.

Authors: R N Jones; R R Packer
Journal: Antimicrob Agents Chemother Date: 1982-12 Impact factor: 5.191

7. Cefotetan, a new cephamycin: comparison of in vitro antimicrobial activity with other cephems, beta-lactamase stability, and preliminary recommendations for disk diffusion testing.

Authors: L W Ayers; R N Jones; A L Barry; C Thornsberry; P C Fuchs; T L Gavan; E H Gerlach; H M Sommers
Journal: Antimicrob Agents Chemother Date: 1982-11 Impact factor: 5.191

8. Impact of cefoperazone therapy on fecal flora.

Authors: M E Mulligan; D M Citron; B T McNamara; S M Finegold
Journal: Antimicrob Agents Chemother Date: 1982-08 Impact factor: 5.191

9. In vitro evaluation of Augmentin by broth microdilution and disk diffusion susceptibility testing: regression analysis, tentative interpretive criteria, and quality control limits.

Authors: P C Fuchs; A L Barry; C Thornsberry; T L Gavan; R N Jones
Journal: Antimicrob Agents Chemother Date: 1983-07 Impact factor: 5.191

10. Sensitivity of 341 non-fermentative gram-negative bacteria to seven beta-lactam antibiotics.

Authors: P C Appelbaum; J Tamim; J Stavitz; R C Aber; G A Pankuch
Journal: Eur J Clin Microbiol Date: 1982-06 Impact factor: 3.267