Literature DB >> 6446873

The effect of social selection on the population dynamics of Huntington's disease.

S Yokoyama, A Templeton.   

Abstract

Wallace (1976) postulated the importance of social selection on the frequency of Huntington's disease. This effect of social selection was studied with respect to the population dynamics of Huntington's disease genes. It is shown that social selection operates mainly through heterozygotes. Existing data indicate that the frequency of Huntington's disease in the population is determined by its social effects.

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Year:  1980        PMID: 6446873     DOI: 10.1111/j.1469-1809.1980.tb01574.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  4 in total

1.  Theories of social selection in human populations.

Authors:  S Yokoyama
Journal:  Am J Hum Genet       Date:  1983-05       Impact factor: 11.025

2.  The mutation rate to Huntington's chorea.

Authors:  M Shaw; A Caro
Journal:  J Med Genet       Date:  1982-06       Impact factor: 6.318

3.  Social selection in human populations: fitness modification of offspring by an affected parent at two loci.

Authors:  S Yokoyama
Journal:  Am J Hum Genet       Date:  1983-07       Impact factor: 11.025

4.  Social selection in human populations. I. Modification of the fitness of offspring by an affected parent.

Authors:  S Yokoyama
Journal:  Am J Hum Genet       Date:  1981-05       Impact factor: 11.025

  4 in total

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