Literature DB >> 6446248

Effects of prostaglandins E-1, E-2, F-1a and F-2a on human sperm motility.

A K Didolkar, D Roychowdhury.   

Abstract

Effects of the addition of 100 micrograms each of prostaglandins E1, E2, F1a and F2a were seen on the motility, fructose utilization and total ATPase activity of human spermatozoa. PGE2 enhanced sperm motility and fructose utilization and decreased the whole sperm ATPase activity. While PGE1 had no effect on any of the parameters studied, PGF1a and PGF2a decreased sperm motility to some extent. Fructose utilization was reduced after PGF1a addition only. No change in the activity of ATPase was observed after treatment with F series of prostaglandins.

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Year:  1980        PMID： 6446248     DOI： 10.1111/j.1439-0272.1980.tb00597.x

Source DB:  PubMed          Journal:  Andrologia        ISSN： 0303-4569            Impact factor:   2.775


  4 in total

Review 1.  Intracavernous prostaglandin E1 in erectile dysfunction.

Authors:  O I Linet; L L Neff
Journal:  Clin Investig       Date:  1994-01

2.  Role of seminal prostaglandins in male fertility. II. Effects of prostaglandin synthesis inhibition on spermatogenesis in man.

Authors:  D Conte; M Nordio; F Romanelli; F Manganelli; P Giovenco; F Dondero; A Isidori
Journal:  J Endocrinol Invest       Date:  1985-08       Impact factor: 4.256

3.  International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.

Authors:  Xavier Norel; Yukihiko Sugimoto; Gulsev Ozen; Heba Abdelazeem; Yasmine Amgoud; Amel Bouhadoun; Wesam Bassiouni; Marie Goepp; Salma Mani; Hasanga D Manikpurage; Amira Senbel; Dan Longrois; Akos Heinemann; Chengcan Yao; Lucie H Clapp
Journal:  Pharmacol Rev       Date:  2020-10       Impact factor: 25.468

4.  Regulation of smooth muscle contractility by the epithelium in rat vas deferens: role of ATP-induced release of PGE2.

Authors:  Ye Chun Ruan; Zhe Wang; Jian Yang Du; Wu Lin Zuo; Jing Hui Guo; Jie Zhang; Zhong Luan Wu; Hau Yin Wong; Yiu Wa Chung; Hsiao Chang Chan; Wen Liang Zhou
Journal:  J Physiol       Date:  2008-08-28       Impact factor: 5.182
  4 in total

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