Literature DB >> 6445196

Effects of trifluoperazine on smooth muscle actomyosin. Short communication.

U Mrwa, J W Peterson, J C Rüegg.   

Abstract

Trifluoperazine (TFP) inhibits superprecipitation and ATPase activity of smooth muscle actomyosin. This effect appears not to be due to the inhibitory effect of TFP on the Ca++-dependent modulator and the myosin light chain kinase, which are known to be cofactors required for activation of smooth muscle actomyosin.

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Year:  1980        PMID: 6445196

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  1 in total

1.  Direct inhibitory effects of some 'calcium-antagonists' and trifluoperazine on the contractile proteins in smooth muscle.

Authors:  M Spedding
Journal:  Br J Pharmacol       Date:  1983-05       Impact factor: 8.739

  1 in total

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