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Literature DB >> 644314

Delayed hypersensitivity in man: effects of systemic anticoagulation.

Abstract

Skin test reactivity, lymphocyte transformation, and mononuclear cell tissue factor generation were evaluated both before and during systemic anticoagulation in 24 volunteers. Anticoagulation with warfarin decreased skin test induration and tissue factor generation, but lymphocyte trnasformation remained unchanged. An intact coagulation mechanism, including tissue factor generation, appears to be important for the development of skin test induration in humans.

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Year: 1978 PMID： 644314 DOI： 10.1126/science.644314

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

20 in total

1. Protein S is inducible by interleukin 4 in T cells and inhibits lymphoid cell procoagulant activity.

Authors: S T Smiley; S N Boyer; M J Heeb; J H Griffin; M J Grusby
Journal: Proc Natl Acad Sci U S A Date: 1997-10-14 Impact factor: 11.205

2. Antigen-induced monocyte procoagulant activity. Requirement for antigen presentation and histocompatibility leukocyte antigen-DR molecules.

Authors: B S Schwartz
Journal: J Clin Invest Date: 1985-09 Impact factor: 14.808

3. Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo.

Authors: Frank M Szaba; Stephen T Smiley
Journal: Blood Date: 2002-02-01 Impact factor: 22.113

4. Fibrin-mediated vascular injury. Identification of fibrin peptides that mediate endothelial cell retraction.

Authors: F N Rowland; M J Donovan; P T Picciano; G D Wilner; D L Kreutzer
Journal: Am J Pathol Date: 1984-12 Impact factor: 4.307

5. Legionella pneumophila and related organisms induce the generation of procoagulant activity by peripheral mononuclear cells in vitro.

Authors: G Miragliotta; N Semeraro; L Marcuccio; D Fumarola
Journal: Infection Date: 1982 Impact factor: 3.553

10. Regulatory roles of T mu and T gamma cells in the collaborative cellular initiation of the extrinsic coagulation pathway by bacterial lipopolysaccharide.

Authors: G A Levy; B S Schwartz; L K Curtiss; T S Edgington
Journal: J Clin Invest Date: 1985-08 Impact factor: 14.808

Delayed hypersensitivity in man: effects of systemic anticoagulation.

1. Protein S is inducible by interleukin 4 in T cells and inhibits lymphoid cell procoagulant activity.

2. Antigen-induced monocyte procoagulant activity. Requirement for antigen presentation and histocompatibility leukocyte antigen-DR molecules.

3. Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo.

4. Fibrin-mediated vascular injury. Identification of fibrin peptides that mediate endothelial cell retraction.

5. Legionella pneumophila and related organisms induce the generation of procoagulant activity by peripheral mononuclear cells in vitro.

Review 6. The role of lymphokines in delayed-type hypersensitivity reactions.

7. Delayed-type hypersensitivity skin reactions in congenital afibrinogenemia lack fibrin deposition and induration.

8. A human T cell clone that mediates the monocyte procoagulant response to specific sensitizing antigen.

9. Role of thrombin and plasmin in development of delayed hypersensitivity reaction in guinea pig skin.

10. Regulatory roles of T mu and T gamma cells in the collaborative cellular initiation of the extrinsic coagulation pathway by bacterial lipopolysaccharide.