The importance of the FSH/LH ratio in ovarian stimulation therapy regime for in vitro fertilization.

In a retrospective study batches of hMG with different FSH/LH ratios, as well as pure FSH were used in two different stimulation protocols (Clomiphene/hMG and hMG only). The aim of this paper was to study the effect and importance of the different FSH/LH ratios if any, in ovarian stimulation during the follicular phase on the success of IVF. The results of our preliminary study indicate that as far as ovarian stimulation with Clomiphene/hMG is concerned, there seems to be no significant beneficial effect on IVF success of using pure FSH or gonadotropin preparations with higher FSH/LH ratios. With gonadotropin only for ovarian stimulation however, the use of high FSH/LH ratio seems to significantly increase the pregnancy rate.