Literature DB >> 6442954

Successful treatment of lethal protozoal infections with the ornithine decarboxylase inhibitor, alpha-difluoromethylornithine.

A Sjoerdsma, J A Golden, P J Schechter, J L Barlow, D V Santi.   

Abstract

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Year:  1984        PMID： 6442954

Source DB:  PubMed          Journal:  Trans Assoc Am Physicians        ISSN： 0066-9458


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  9 in total

Review 1.  Recent advances in the biochemistry of polyamines in eukaryotes.

Authors:  A E Pegg
Journal:  Biochem J       Date:  1986-03-01       Impact factor: 3.857

2.  Activity of lipid-soluble inhibitors of dihydrofolate reductase against Pneumocystis carinii in culture and in a rat model of infection.

Authors:  S F Queener; M S Bartlett; M A Jay; M M Durkin; J W Smith
Journal:  Antimicrob Agents Chemother       Date:  1987-09       Impact factor: 5.191

3.  Polyamine regulation of heat-shock-induced spermidine N1-acetyltransferase activity.

Authors:  D J Fuller; S W Carper; L Clay; J R Chen; E W Gerner
Journal:  Biochem J       Date:  1990-05-01       Impact factor: 3.857

4.  Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone).

Authors:  A J Bitonti; J A Dumont; P P McCann
Journal:  Biochem J       Date:  1986-08-01       Impact factor: 3.857

5.  Polyamine depletion and growth inhibition of Cryptococcus neoformans by alpha-difluoromethylornithine and cyclohexylamine.

Authors:  M A Pfaller; J Riley; T Gerarden
Journal:  Mycopathologia       Date:  1990-10       Impact factor: 2.574

6.  Growth inhibition of pathogenic yeast isolates by alpha-difluoromethylornithine: an inhibition of ornithine decarboxylase.

Authors:  M A Pfaller; T Gerarden; J Riley
Journal:  Mycopathologia       Date:  1987-04       Impact factor: 2.574

7.  Decarboxylation of alpha-difluoromethylornithine by ornithine decarboxylase.

Authors:  A E Pegg; K A McGovern; L Wiest
Journal:  Biochem J       Date:  1987-01-01       Impact factor: 3.857

8.  Alterations in human circulating and bone marrow mononuclear cell polyamine levels in hematologic malignancies as a consequence of difluoromethylornithine administration.

Authors:  A M Maddox; E J Freireich; M J Keating; K F Frasier-Scott; M K Haddox
Journal:  Invest New Drugs       Date:  1988-06       Impact factor: 3.850

9.  Method of testing the susceptibility of Pneumocystis carinii to antimicrobial agents in vitro.

Authors:  M T Cushion; D Stanforth; M J Linke; P D Walzer
Journal:  Antimicrob Agents Chemother       Date:  1985-12       Impact factor: 5.191
  9 in total

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