Literature DB >> 6441947

Residual effects of prolonged cannabis treatment on shuttle-box avoidance in the rat.

A Stiglick, M E Llewellyn, H Kalant.   

Abstract

Chronic oral administration of cannabis extract to rats was examined for its residual effects on shuttle-box avoidance learning. In experiment 1 avoidance learning was assessed in rats that had been tested previously on other behavioral tests. Chronic treatment (3 months) facilitated the learning of shuttle-box avoidance in cannabis-treated animals relative to vehicle controls. In experiment 2 very similar results were obtained in naive rats. These and other residual effects of chronic cannabis treatment are similar to the effects of hippocampal lesions.

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Year:  1984        PMID: 6441947     DOI: 10.1007/bf00431452

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  12 in total

1.  Locomotor, avoidance,and maze behavior in rats with selective disruption of hippocampal output.

Authors:  T Myhrer
Journal:  J Comp Physiol Psychol       Date:  1975-09

2.  EFFECT OF BILATERAL HIPPOCAMPAL ABLATION ON DRL PERFORMANCE.

Authors:  C V CLARK; R L ISAACSON
Journal:  J Comp Physiol Psychol       Date:  1965-02

3.  Damage to hippocampus and hippocampal connections: effects on DRL and spontaneous alternation.

Authors:  C T Johnson; D S Olton; F H Gage; P G Jenko
Journal:  J Comp Physiol Psychol       Date:  1977-06

4.  Differential performance of hippocampally ablated rats on nondiscriminated and discriminated DRL schedules.

Authors:  E J Rickert; T L Bennett; G J Anderson; J Corbett; L Smith
Journal:  Behav Biol       Date:  1973-05

5.  The metabolism and excretion of delta 9-tetrahydrocannabinol in the rat.

Authors:  H A Klausner; J V Dingell
Journal:  Life Sci I       Date:  1971-01-01

6.  Retrograde amnesia and hippocampal stimulation: dependence upon the nature of associations formed during conditioning.

Authors:  B S Kapp; M Gallagher; B K Holmquist; C L Theall
Journal:  Behav Biol       Date:  1978-09

7.  Hippocampal connections and spatial discrimination.

Authors:  D S Olton; J A Walker; F H Gage
Journal:  Brain Res       Date:  1978-01-13       Impact factor: 3.252

8.  Learning impairment in the radial-arm maze following prolonged cannabis treatment in rats.

Authors:  A Stiglick; H Kalant
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

9.  Residual learning deficit after heavy exposure to cannabis or alcohol in rats.

Authors:  K A Fehr; H Kalant; A E LeBlanc
Journal:  Science       Date:  1976-06-18       Impact factor: 47.728

10.  Residual effects of prolonged cannabis administration on exploration and DRL performance in rats.

Authors:  A Stiglick; H Kalant
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

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  6 in total

1.  Residual effects of chronic cannabis treatment on behavior in mature rats.

Authors:  A Stiglick; H Kalant
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

Review 2.  The dual neuroprotective-neurotoxic profile of cannabinoid drugs.

Authors:  Yosef Sarne; Fadi Asaf; Miriam Fishbein; Mikhal Gafni; Ora Keren
Journal:  Br J Pharmacol       Date:  2011-08       Impact factor: 8.739

Review 3.  The influence of marijuana use on neurocognitive functioning in adolescents.

Authors:  Alecia D Schweinsburg; Sandra A Brown; Susan F Tapert
Journal:  Curr Drug Abuse Rev       Date:  2008-01

4.  Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol.

Authors:  G C Chan; T R Hinds; S Impey; D R Storm
Journal:  J Neurosci       Date:  1998-07-15       Impact factor: 6.167

5.  Oral THC produces minimal behavioral alterations in preadolescent rats.

Authors:  Diana Dow-Edwards; Ning Zhao
Journal:  Neurotoxicol Teratol       Date:  2008-03-21       Impact factor: 3.763

6.  Failure of acute and chronic administration of delta 9-tetrahydrocannabinol to affect the repeated acquisition of serial position response in pigeons.

Authors:  D E McMillan
Journal:  Pavlov J Biol Sci       Date:  1988 Apr-Jun
  6 in total

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