Literature DB >> 6441619

[In vitro activation by dithiothreitol and thioredoxins of carbamyl phosphate synthetase-I in rat liver].

C Gautier, Z Habechi, A P Balangé, R Vaillant.   

Abstract

Carbamyl phosphate synthetase-I (CPS-I; EC 6.3.4.16), a mitochondrial enzyme of the urea-cycle, was studied in deactivated extracts of rat liver. It has been found to be activated in vitro by dithiothreitol (DTT) and Mg2+ ions. After reduction by DTT, thioredoxins, isolated from rat liver, were able to activate CPS-I by 468%.

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Year:  1984        PMID: 6441619

Source DB:  PubMed          Journal:  C R Acad Sci III        ISSN: 0764-4469


  2 in total

1.  Development and hormonal control of thioredoxin and the thioredoxin-reductase system in the rat liver during the perinatal period.

Authors:  J Demarquoy; A Fairand; R Vaillant; C Gautier
Journal:  Experientia       Date:  1991-05-15

2.  Role of Cys-1327 and Cys-1337 in redox sensitivity and allosteric monitoring in human carbamoyl phosphate synthetase.

Authors:  Emily J Hart; Susan G Powers-Lee
Journal:  J Biol Chem       Date:  2008-12-23       Impact factor: 5.157

  2 in total

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