Literature DB >> 6439570

Evidence for an activating effect of tabernanthine on rat brain catecholamine synthesis and elimination.

M Prioux-Guyonneau, E Mocaër-Cretet, Y Cohen, C Jacquot.   

Abstract

Tabernanthine increased the synthesis and elimination of catecholamines (CA) in the striatum and the rest of the brain, but not in the hypothalamus. These data provide evidence that tabernanthine may activate CA turnover of some brain structures by acting at 2 steps of the metabolic pathway. The results are discussed in relation to a central stimulating action and a hypoxia antagonistic effect of this drug.

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Year:  1984        PMID: 6439570     DOI: 10.1007/bf01951904

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  10 in total

Review 1.  Effect of amphetamine-type psychostimulants on brain metabolism.

Authors:  C J Estler
Journal:  Adv Pharmacol Chemother       Date:  1975

2.  THE DISTRIBUTION OF DOPAMINE AND DOPA IN VARIOUS ANIMALS AND A METHOD FOR THEIR DETERMINATION IN DIVERSE BIOLOGICAL MATERIAL.

Authors:  A H ANTON; D F SAYRE
Journal:  J Pharmacol Exp Ther       Date:  1964-09       Impact factor: 4.030

3.  A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines.

Authors:  A H ANTON; D F SAYRE
Journal:  J Pharmacol Exp Ther       Date:  1962-12       Impact factor: 4.030

4.  [SOME PHARMACOLOGICAL PROPERTIES OF 12 NATURAL AND 11 PARTIALLY SYNTHETICALLY DERIVED INDOLE ALKALOIDS FROM TROPICAL APOCYANACEAE OF THE SUB-TRIBE TABERNAEMONTANINAE].

Authors:  G ZETLER
Journal:  Arzneimittelforschung       Date:  1964-12

5.  Improved technique for the fluorimetric estimation of catecholamines.

Authors:  U von EULER; F LISHAJKO
Journal:  Acta Physiol Scand       Date:  1961-04

6.  Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase.

Authors:  A Carlsson; J N Davis; W Kehr; M Lindqvist; C V Atack
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

7.  Refractory period and strophanthin actions, as influenced by four indole alkaloids and two synthetic azepinoindoles.

Authors:  G Zetler; W Lessau
Journal:  Pharmacology       Date:  1972       Impact factor: 2.547

8.  Application of steady state kinetics to the estimation of synthesis rate and turnover time of tissue catecholamines.

Authors:  B B Brodie; E Costa; A Dlabac; N H Neff; H H Smookler
Journal:  J Pharmacol Exp Ther       Date:  1966-12       Impact factor: 4.030

9.  Effect of tabernanthine on the turnover time of brain catecholamines in normal and hypobaric hypoxic rats.

Authors:  E Cretet; M Prioux-Guyonneau; C Jacquot; H Sentenac; J Wepierre
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-08       Impact factor: 3.000

10.  Changes in brain 5-hydroxytryptamine metabolism induced by hypobaric hypoxia.

Authors:  M Prioux-Guyonneau; E Mocaër-Cretet; F Redjimi-Hafsi; C Jacquot
Journal:  Gen Pharmacol       Date:  1982
  10 in total

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