Literature DB >> 6438278

Anticonvulsant drugs alter plasma tryptophan concentrations in epileptic patients: implications for antiepileptic action and mental function.

J A Pratt, P Jenner, A L Johnson, S D Shorvon, E H Reynolds.   

Abstract

In epileptic patients carbamazepine and diphenylhydantoin have opposite effects on whole and free plasma tryptophan concentrations, the former elevating and the latter depressing them. It is unlikely that these observations relate to the similar anti-epileptic properties of these two drugs but they may relate to their different effects on mental function and mood.

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Year:  1984        PMID： 6438278      PMCID： PMC1028047          DOI： 10.1136/jnnp.47.10.1131

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  13 in total

1.  Influence of various drugs on the binding of L-tryptophan to human serum albumin.

Authors:  W E Müller; U Wollert
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1975-03

2.  Anticonvulsant drugs and mental symptoms: a review.

Authors:  M R Trimble; E H Reynolds
Journal:  Psychol Med       Date:  1976-05       Impact factor: 7.723

3.  Serotonin metabolism in human epilepsy: the influence of anticonvulsant drugs.

Authors:  D Chadwick; P Jenner; E H Reynolds
Journal:  Ann Neurol       Date:  1977-03       Impact factor: 10.422

4.  A method for the estimation of free and total acid-soluble plasma tryptophan using an ultrafiltration technique.

Authors:  E G Eccleston
Journal:  Clin Chim Acta       Date:  1973-10-30       Impact factor: 3.786

5.  An isothermal GLC determination of the plasma levels of carbamazepine, diphenylhydantoin, phenobarbitone and primidone.

Authors:  P A Toseland; J Grove; D J Berry
Journal:  Clin Chim Acta       Date:  1972-05       Impact factor: 3.786

Review 6.  Serum levels of anticonvulsant drugs. Interpretation and clinical value.

Authors:  E H Reynolds
Journal:  Pharmacol Ther       Date:  1980       Impact factor: 12.310

7.  Inhibition of rat liver tryptophan pyrrolase activity and elevation of brain tryptophan concentration by administration of antidepressants.

Authors:  A A Badawy; M Evans
Journal:  Biochem Pharmacol       Date:  1981-06-01       Impact factor: 5.858

8.  Relationships between plasma, CSF and brain tryptophan.

Authors:  G Curzon
Journal:  J Neural Transm Suppl       Date:  1979

9.  Psychotropic effects of carbamazepine in epilepsy: a double-blind comparison with phenytoin.

Authors:  C B Dodrill; A S Troupin
Journal:  Neurology       Date:  1977-11       Impact factor: 9.910

10.  Tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human cerebrospinal fluid: interrelationships and the influence of age, sex, epilepsy and anticonvulsant drugs.

Authors:  S N Young; S Gauthier; G M Anderson; W C Purdy
Journal:  J Neurol Neurosurg Psychiatry       Date:  1980-05       Impact factor: 10.154
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  9 in total

Review 1.  Anticonvulsant-induced psychiatric disorders. The role of forced normalisation.

Authors:  M R Trimble
Journal:  Drug Saf       Date:  1996-09       Impact factor: 5.606

2.  Proceedings of the British Pharmacological Society. Leeds, 12th-14th July 1989. Abstracts.

Authors: 
Journal:  Br J Pharmacol       Date:  1989-10       Impact factor: 8.739

Review 3.  Adverse neuropsychiatric effects of anticonvulsant drugs.

Authors:  E H Reynolds; M R Trimble
Journal:  Drugs       Date:  1985-06       Impact factor: 9.546

Review 4.  Antiepileptic drug toxicity: definition and mechanism of action.

Authors:  E Beghi; R Di Mascio
Journal:  Ital J Neurol Sci       Date:  1986-04

5.  Inhibition by carbamazepine of various ion channels-mediated catecholamine secretion in cultured bovine adrenal medullary cells.

Authors:  R Yoshimura; N Yanagihara; T Terao; K Minami; K Abe; F Izumi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1995-09       Impact factor: 3.000

Review 6.  Complex partial seizures and depression.

Authors:  Brian A Greenlee; Richard B Ferrell; Christopher I Kauffman; Thomas W McAllister
Journal:  Curr Psychiatry Rep       Date:  2003-10       Impact factor: 5.285

7.  Anxiolytic effect of carbamazepine in the elevated plus-maze: possible role of adenosine.

Authors:  H Zangrossi; J R Leite; F G Graeff
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

Review 8.  Serotonin and sudden unexpected death in epilepsy.

Authors:  Alexandra N Petrucci; Katelyn G Joyal; Benton S Purnell; Gordon F Buchanan
Journal:  Exp Neurol       Date:  2019-12-19       Impact factor: 5.330

9.  Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration.

Authors:  Elena L Paley; George Perry
Journal:  Nutrients       Date:  2018-03-26       Impact factor: 5.717
  9 in total

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