Literature DB >> 6437858

Molecular mechanism for the production of multiple forms of MM creatine kinase.

M B Perryman, J D Knell, R Roberts.   

Abstract

Incubation of human, canine or rabbit MM creatine kinase with carboxypeptidase-N or B resulted in the production of 2 additional enzyme forms with increased anodal migration on polyacrylamide gels. The C-terminal amino acid of tissue MM creatine kinase from all 3 species was shown to be lysine, a specific substrate for carboxypeptidase-N and B.

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Year:  1984        PMID： 6437858     DOI： 10.1007/bf01946672

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  CARBOXYPEPTIDASE IN BLOOD AND OTHER FLUIDS. I. PROPERTIES, DISTRIBUTION, AND PARTIAL PURIFICATION OF THE ENZYME.

Authors:  E G ERDOES; E M SLOANE; I M WOHLER
Journal:  Biochem Pharmacol       Date:  1964-06       Impact factor: 5.858

2.  Carboxy-peptidase B. 4. Purification and characterization of the porcine enzyme.

Authors:  J E FOLK; K A PIEZ; W R CARROLL; J A GLADNER
Journal:  J Biol Chem       Date:  1960-08       Impact factor: 5.157

3.  Isoelectric focusing and hybridisation experiments on creatine kinase (EC 2.7.3.2).

Authors:  R A Wevers; R J Wolters; J B Soons
Journal:  Clin Chim Acta       Date:  1977-07-15       Impact factor: 3.786

4.  A study on the dimeric structure of creatine kinase (EC 2.7.3.2).

Authors:  R A Wevers; H P Olthuis; J C Van Niel; M G Van Wilgenburg; J B Soons
Journal:  Clin Chim Acta       Date:  1977-03-15       Impact factor: 3.786

5.  Quantification of serum creatine phosphokinase isoenzyme activity.

Authors:  R Roberts; P D Henry; S A Witteeveen; B E Sobel
Journal:  Am J Cardiol       Date:  1974-05-06       Impact factor: 2.778

6.  Comparative studies on human carboxypeptidases B and N.

Authors:  T J McKay; A W Phelan; T H Plummer
Journal:  Arch Biochem Biophys       Date:  1979-10-15       Impact factor: 4.013

7.  An improved basis for enzymatic estimation of infarct size.

Authors:  R Roberts; P D Henry; B E Sobel
Journal:  Circulation       Date:  1975-11       Impact factor: 29.690

8.  Postsynthetic variants of creatine kinase MM.

Authors:  W G Yasmineh; M K Yamada; J N Cohn
Journal:  J Lab Clin Med       Date:  1981-07

9.  Molecular heterogeneity of creatine kinase isoenzymes.

Authors:  M B Perryman; A W Strauss; T L Buettner; R Roberts
Journal:  Biochim Biophys Acta       Date:  1983-09-28

10.  Further heterogeneity demonstrated for serum creatine kinase isoenzyme MM.

Authors:  J P Chapelle; C Heusghem
Journal:  Clin Chem       Date:  1980-03       Impact factor: 8.327
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  1 in total

Review 1.  Creatine kinase in the dog: a review.

Authors:  M Aktas; D Auguste; H P Lefebvre; P L Toutain; J P Braun
Journal:  Vet Res Commun       Date:  1993       Impact factor: 2.459
  1 in total

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