Literature DB >> 6437719

Lithium causing a serious sinus-node dysfunction at therapeutic doses.

G Montalescot, Y Levy, D Farge, L Brochard, B Fantin, C Arnoux, P Y Hatt.   

Abstract

The cardiovascular effects of lithium have been indexed in literature since 1900, most frequently in cases of intoxication. We recently studied the exceptional case of a patient showing a serious sinus node dysfunction during lithium treatment. The serum lithium levels were always within the therapeutic range. After two endocardial explorations and withdrawal of lithium, we found that the sinus node dysfunction was due to lithium and reversible after withdrawal of it. Some ignored dysfunctions could exist with a regularly controlled treatment.

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Year:  1984        PMID： 6437719     DOI： 10.1002/clc.4960071113

Source DB:  PubMed          Journal:  Clin Cardiol        ISSN： 0160-9289            Impact factor:   2.882


  5 in total

1.  Sinus node dysfunction during long-term lithium treatment.

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Review 2.  Cancer risk from inorganics.

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3.  Lithium-induced sinus node disease at therapeutic concentrations: linking lithium-induced blockade of sodium channels to impaired pacemaker activity.

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Journal:  Can J Cardiol       Date:  2007-03-01       Impact factor: 5.223

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Journal:  J Anaesthesiol Clin Pharmacol       Date:  2011-10

Review 5.  Inherited and Acquired Rhythm Disturbances in Sick Sinus Syndrome, Brugada Syndrome, and Atrial Fibrillation: Lessons from Preclinical Modeling.

Authors:  Laura Iop; Sabino Iliceto; Giovanni Civieri; Francesco Tona
Journal:  Cells       Date:  2021-11-15       Impact factor: 6.600
  5 in total

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