| Literature DB >> 6436885 |
J Shimizu, S Nomura, H Kuno, T Nakazawa.
Abstract
This experiment investigated the effect of imipramine on water wheel turning behavior in relation to the water temperature and the wheel load. It was shown that the higher the water temperature, the more the mice rotated the wheel, and the greater the wheel load, the less mice rotated it. However, these factors did not reduce the effect of imipramine, which increased the number of responses. It was suggested that the water wheel test shows promise as a screening test for antidepressants.Entities:
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Year: 1984 PMID： 6436885 DOI： 10.1007/bf00432017
Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530