Literature DB >> 643622

Xeroderma pigmentosum fibroblasts of the D group lack an apurinic DNA endonuclease species with a low apparent Km.

U Kuhnlein, B Lee, E E Penhoet, S Linn.   

Abstract

Apurinic DNA endonuclease activity from cultured human fibroblasts was resolved into two species by phosphocellulose chromatography. The species had sedimentation coefficients of 3.3 S and 2.8 S and apparent Km's for apurinic sites of 5 and 44 nM, respectively. The low Km species was absent from extracts of cell lines XP5BE, XP6BE and XP7BE of xeroderma pigmentosum complementation group D.

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Year:  1978        PMID： 643622      PMCID： PMC342035          DOI： 10.1093/nar/5.3.951

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  21 in total

1.  Statistical estimations in enzyme kinetics.

Authors:  G N WILKINSON
Journal:  Biochem J       Date:  1961-08       Impact factor: 3.857

2.  Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates.

Authors:  K H Kraemer; H G Coon; R A Petinga; S F Barrett; A E Rahe; J H Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

3.  Restoration of ultraviolet-induced unscheduled DNA synthesis of xeroderma pigmentosum cells by the concomitant treatment with bacteriophage T4 endonuclease V and HVJ (Sendai virus).

Authors:  K Tanaka; M Sekiguchi; Y Okada
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

4.  Five complementation groups in xeroderma pigmentosum.

Authors:  K H Kraemer; E A De Weerd-Kastelein; J H Robbins; W Keijzer; S F Barrett; R A Petinga; D Bootsma
Journal:  Mutat Res       Date:  1975-12       Impact factor: 2.433

5.  Photoreactivation of pyrimidine dimers in the DNA of normal and xeroderma pigmentosum cells.

Authors:  B M Sutherland; R Oliver; C O Fuselier; J C Sutherland
Journal:  Biochemistry       Date:  1976-01-27       Impact factor: 3.162

6.  Heat-induced deamination of cytosine residues in deoxyribonucleic acid.

Authors:  T Lindahl; B Nyberg
Journal:  Biochemistry       Date:  1974-07-30       Impact factor: 3.162

7.  Repair of DNA damaged by alkylating carcinogens is defective in xeroderma pigmentosum-derived fibroblasts.

Authors:  R Goth-Goldstein
Journal:  Nature       Date:  1977-05-05       Impact factor: 49.962

8.  Sister chromatid exchanges induced by mutagenic carcinogens in normal and xeroderma pigmentosum cells.

Authors:  S Wolff; B Rodin; J E Cleaver
Journal:  Nature       Date:  1977-01-27       Impact factor: 49.962

9.  A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses.

Authors:  W C Russell; C Newman; D H Williamson
Journal:  Nature       Date:  1975-02-06       Impact factor: 49.962

10.  Rate of depurination of native deoxyribonucleic acid.

Authors:  T Lindahl; B Nyberg
Journal:  Biochemistry       Date:  1972-09-12       Impact factor: 3.162
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  17 in total

1.  Apurinic acid endonuclease activity from mouse epidermal cells.

Authors:  G Ludwig; H W Thielmann
Journal:  Nucleic Acids Res       Date:  1979-06-25       Impact factor: 16.971

2.  Apurinic endonuclease activity from wild-type and repair-deficient mei-9 Drosophila ovaries.

Authors:  S Venugopal; S N Guzder; W A Deutsch
Journal:  Mol Gen Genet       Date:  1990-05

3.  DNA binding activity from cultured human fibrolasts that is specific for partially depurinated DNA and that inserts purines into apurinic sites.

Authors:  W A Deutsch; S Linn
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

4.  Purification and amino-terminal amino acid sequence of an apurinic/apyrimidinic endonuclease from calf thymus.

Authors:  W D Henner; N P Kiker; T J Jorgensen; J N Munck
Journal:  Nucleic Acids Res       Date:  1987-07-24       Impact factor: 16.971

5.  Purification and characterization of a novel human acidic nuclease/intra-cyclobutyl-pyrimidine-dimer-DNA phosphodiesterase.

Authors:  K S Famulski; M Liuzzi; S Bashir; R Mirzayans; M C Paterson
Journal:  Biochem J       Date:  2000-02-01       Impact factor: 3.857

6.  Role of active site tyrosines in dynamic aspects of DNA binding by AP endonuclease.

Authors:  Luisa F Melo; Sophia T Mundle; Michael H Fattal; N Edel O'Regan; Phyllis R Strauss
Journal:  DNA Repair (Amst)       Date:  2007-01-10

7.  Xeroderma pigmentosum patients from Germany: repair capacity of 45 XP fibroblast strains of the Mannheim XP Collection as measured by colony-forming ability and unscheduled DNA synthesis following treatment with methyl methanesulfonate and N-methyl-N-nitrosourea.

Authors:  H W Thielmann; L Edler; S Friemel
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

8.  Enhanced expression of mitochondrial genes in xeroderma pigmentosum fibroblast strains from various complementation groups.

Authors:  M Rothe; D Werner; H W Thielmann
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553

9.  The response of ataxia telangiectasia cells to bleomycin.

Authors:  A R Lehmann; S Stevens
Journal:  Nucleic Acids Res       Date:  1979       Impact factor: 16.971

10.  Characterization of a depurinated-DNA purine-base-insertion activity from Drosophila.

Authors:  W A Deutsch; A L Spiering
Journal:  Biochem J       Date:  1985-11-15       Impact factor: 3.857
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