Literature DB >> 6436049

Neurotoxic effects of endogenous materials: quinolinic acid, L-pyroglutamic acid, and thyroid releasing hormone (TRH).

E G McGeer, E Singh.   

Abstract

The previously reported, dose-related, and selective neurotoxic action of 100 to 200 nmol quinolinic acid on intrastriatal injection was confirmed. A slight neurotoxicity was obtained with 250 nmol thyroid releasing hormone but not with a similar dose of L-pyroglutamic acid.

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Year:  1984        PMID： 6436049     DOI： 10.1016/0014-4886(84)90197-3

Source DB:  PubMed          Journal:  Exp Neurol        ISSN： 0014-4886            Impact factor:   5.330


  5 in total

1.  Hypodense eosinophils and interleukin 5 activity in the blood of patients with the eosinophilia-myalgia syndrome.

Authors:  W F Owen; J Petersen; D M Sheff; R D Folkerth; R J Anderson; J M Corson; A L Sheffer; K F Austen
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

2.  L-pyroglutamic acid inhibits energy production and lipid synthesis in cerebral cortex of young rats in vitro.

Authors:  A R Silva; C G Silva; C Ruschel; C Helegda; A T Wyse; C M Wannmacher; M Wajner; C S Dutra-Filho
Journal:  Neurochem Res       Date:  2001-12       Impact factor: 3.996

3.  Neurochemical effects of L-pyroglutamic acid.

Authors:  C F de Mello; D D De La Vega; L T Pizutti; F P Lopes; M A Rubin; J G Homerich; C R Melo; J E Somer; D O Souza; M Wajner
Journal:  Neurochem Res       Date:  1995-12       Impact factor: 3.996

Review 4.  Substrate channeling in proline metabolism.

Authors:  Benjamin W Arentson; Nikhilesh Sanyal; Donald F Becker
Journal:  Front Biosci (Landmark Ed)       Date:  2012-01-01

Review 5.  Quinolinic acid: an endogenous neurotoxin with multiple targets.

Authors:  Rafael Lugo-Huitrón; Perla Ugalde Muñiz; Benjamin Pineda; José Pedraza-Chaverrí; Camilo Ríos; Verónica Pérez-de la Cruz
Journal:  Oxid Med Cell Longev       Date:  2013-09-05       Impact factor: 6.543
  5 in total

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