Literature DB >> 6435904

Antitumor-promoting activity of glycyrrhetic acid in mouse skin tumor formation induced by 7,12-dimethylbenz[a]anthracene plus teleocidin.

H Nishino, K Kitagawa, A Iwashima.   

Abstract

Glycyrrhetic acid inhibited the action of tumor promoter in vitro and in vivo. Glycyrrhetic acid inhibited the increased phospholipid metabolism of cultured cells induced by tumor promoters, 12-O-tetradecanoylphorbol-13-acetate or teleocidin, and it markedly suppressed the promoting effect of teleocidin on skin tumor formation in mice initiated with 7,12-dimethylbenz[a]anthracene.

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Year:  1984        PMID： 6435904     DOI： 10.1093/carcin/5.11.1529

Source DB:  PubMed          Journal:  Carcinogenesis        ISSN： 0143-3334            Impact factor:   4.944


  3 in total

1.  Paeoniflorin, a novel heat shock protein-inducing compound.

Authors:  Dai Yan; Kiyoto Saito; Yuri Ohmi; Noriyo Fujie; Kenzo Ohtsuka
Journal:  Cell Stress Chaperones       Date:  2004       Impact factor: 3.667

2.  The synthesis of glycyrrhetinic acid derivatives containing a nitrogen heterocycle and their antiproliferative effects in human leukemia cells.

Authors:  Yuan Gao; Xin Guo; Xiaojing Li; Dan Liu; Dandan Song; Ye Xu; Ming Sun; Yongkui Jing; Linxiang Zhao
Journal:  Molecules       Date:  2010-06-21       Impact factor: 4.411

3.  Effects of nine active ingredients in Chinese herbal medicine sho-saiko-to on 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide mutagenicity.

Authors:  M Ohtsuka; K Fukuda; H Yano; M Kojiro
Journal:  Jpn J Cancer Res       Date:  1995-12
  3 in total

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