| Literature DB >> 6435674 |
R Nayar, L D Mayer, M J Hope, P R Cullis.
Abstract
The ionophoretic capabilities of dioleoylphosphatidic acid (DOPA) for transporting calcium across phospholipid bilayers have been investigated. Calcium uptake by large unilamellar vesicles is shown to depend on the presence of DOPA. This uptake is sensitive to the nature and concentration of calcium chelators in the vesicle interior, indicating that accumulation results from DOPA-mediated translocation of calcium across the membrane. Further, it is shown that characteristics of DOPA-mediated Ca2+ uptake are similar to those observed for the fungal calcium ionophore, A23187.Entities:
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Year: 1984 PMID： 6435674 DOI： 10.1016/0005-2736(84)90438-3
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002