Literature DB >> 6434486

Nonlysozyme antibacterial factor in human tears. Fact or fiction?

P T Janssen, H L Muytjens, O P van Bijsterveld.   

Abstract

The existence of nonlysozyme antibacterial activity in tear fluid was reinvestigated. Tear fluid was fractionated by ultrafiltration and affinity chromatography. The antibacterial activity, detected in native tear fluid, coincided with the presence of lysozyme in the fractions. No antibacterial activity could be detected by agar diffusion in the fractions that should contain the low molecular mass antibacterial factors of tear fluid, reported in the literature.

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Year:  1984        PMID: 6434486

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  3 in total

Review 1.  Antimicrobial compounds in tears.

Authors:  Alison M McDermott
Journal:  Exp Eye Res       Date:  2013-07-20       Impact factor: 3.467

2.  Secretory phospholipase A2 is the principal bactericide for staphylococci and other gram-positive bacteria in human tears.

Authors:  X D Qu; R I Lehrer
Journal:  Infect Immun       Date:  1998-06       Impact factor: 3.441

3.  A cleavage-potentiated fragment of tear lacritin is bactericidal.

Authors:  Robert L McKown; Erin V Coleman Frazier; Kaneil K Zadrozny; Andrea M Deleault; Ronald W Raab; Denise S Ryan; Rose K Sia; Jae K Lee; Gordon W Laurie
Journal:  J Biol Chem       Date:  2014-06-18       Impact factor: 5.157

  3 in total

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