Literature DB >> 6434404

Release of arachidonic acid: a new function of the late complement components.

M Betz, G M Hänsch.   

Abstract

Incubation of Ehrlich-ascites cells with sublytic complement doses results in degradation of membrane phospholipids and release of arachidonic acid. Phospholipase A2 blockers inhibit arachidonic acid release indicating a phospholipase dependent cleavage of the phospholipids. Phospholipase A2 is apparently activated during complement-membrane interaction, representing a new reactivity of the late complement components.

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Year:  1984        PMID: 6434404     DOI: 10.1016/S0171-2985(84)80024-8

Source DB:  PubMed          Journal:  Immunobiology        ISSN: 0171-2985            Impact factor:   3.144


  5 in total

1.  Human rheumatoid synovial cell stimulation by the membrane attack complex and other pore-forming toxins in vitro: the role of calcium in cell activation.

Authors:  R H Daniels; B D Williams; B P Morgan
Journal:  Immunology       Date:  1990-11       Impact factor: 7.397

2.  Complement profiles in human skin lymph during the course of irritant contact dermatitis.

Authors:  C U Brand; P J Späth; T Hunziker; A Limat; L R Braathen
Journal:  Arch Dermatol Res       Date:  1994       Impact factor: 3.017

3.  The recovery of human polymorphonuclear leucocytes from sublytic complement attack is mediated by changes in intracellular free calcium.

Authors:  B P Morgan; A K Campbell
Journal:  Biochem J       Date:  1985-10-01       Impact factor: 3.857

4.  A role for thromboxane in complement-mediated glomerular injury.

Authors:  A V Cybulsky; W Lieberthal; R J Quigg; H G Rennke; D J Salant
Journal:  Am J Pathol       Date:  1987-07       Impact factor: 4.307

Review 5.  Infectious diseases associated with complement deficiencies.

Authors:  J E Figueroa; P Densen
Journal:  Clin Microbiol Rev       Date:  1991-07       Impact factor: 26.132

  5 in total

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