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Literature DB >> 6434217

Congenital osteopetrotic mutations as probes of the origin, structure, and function of osteoclasts.

Abstract

Progress has been made in recent years on the cell biology of the osteoclast and the pathogenesis of congenital osteopetrosis. New information is critically evaluated and summarized with respect to the origin, structure, and function of osteoclasts with special reference to osteopetroses. A broader perspective emerges from which to consider the biology of osteoclasts, the heterogeneities in the osteopetroses, and the value of each in elucidating the other, along with treatment of the disorder.

Entities: Disease

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Year: 1984 PMID： 6434217

Source DB: PubMed Journal: Clin Orthop Relat Res ISSN： 0009-921X Impact factor: 4.176

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Cited

17 in total

Review 1. New knowledge on critical osteoclast formation and activation pathways from study of rare genetic diseases of osteoclasts: focus on the RANK/RANKL axis.

Authors: J C Crockett; D J Mellis; D I Scott; M H Helfrich
Journal: Osteoporos Int Date: 2010-05-11 Impact factor: 4.507

2. Different tartrate sensitivity and pH optimum for two isoenzymes of acid phosphatase in osteoclasts. An electron-microscopic enzyme-cytochemical study.

Authors: T Akisaka; G P Subita; H Kawaguchi; Y Shigenaga
Journal: Cell Tissue Res Date: 1989-01 Impact factor: 5.249

3. Immunophenotypic differences between osteoclasts and macrophage polykaryons: immunohistological distinction and implications for osteoclast ontogeny and function.

Authors: N A Athanasou; J Quinn
Journal: J Clin Pathol Date: 1990-12 Impact factor: 3.411

4. Bone marrow transplantation in precocious osteopetrosis.

Authors: N W Nisbet
Journal: Br Med J (Clin Res Ed) Date: 1987-02-21

5. Survival and resorptive activity of chick osteoclasts in culture.

Authors: S J Jones; N N Ali; A Boyde
Journal: Anat Embryol (Berl) Date: 1986

6. Osteoclast generation from human fetal bone marrow in cocultures with murine fetal long bones. A model for in vitro study of human osteoclast formation and function.

Authors: M H Helfrich; C W Thesingh; R H Mieremet; A S van Iperen-van Gent
Journal: Cell Tissue Res Date: 1987-07 Impact factor: 5.249

Congenital osteopetrotic mutations as probes of the origin, structure, and function of osteoclasts.

Review 1. New knowledge on critical osteoclast formation and activation pathways from study of rare genetic diseases of osteoclasts: focus on the RANK/RANKL axis.

2. Different tartrate sensitivity and pH optimum for two isoenzymes of acid phosphatase in osteoclasts. An electron-microscopic enzyme-cytochemical study.

3. Immunophenotypic differences between osteoclasts and macrophage polykaryons: immunohistological distinction and implications for osteoclast ontogeny and function.

4. Bone marrow transplantation in precocious osteopetrosis.

5. Survival and resorptive activity of chick osteoclasts in culture.

6. Osteoclast generation from human fetal bone marrow in cocultures with murine fetal long bones. A model for in vitro study of human osteoclast formation and function.

7. The regulation of hemopoiesis in the spleen.

8. Malignant osteopetrosis: c-src kinase is not reduced in fibroblasts.

9. Failure of calcitriol treatment in a patient with malignant osteopetrosis.

10. The effects of parathyroid hormone or 1,25-dihydroxyvitamin D3 on monocyte-osteoclast fusion.