| Literature DB >> 6433372 |
R T Joffe, P W Gold, T W Uhde, R M Post.
Abstract
A thyrotropin (thyroid-stimulating hormone; TSH) stimulation test with thyroid-releasing hormone (TRH) was performed on six patients with a DSM-III diagnosis of major depressive disorder, both before and during a trial of carbamazepine. Carbamazepine, an anticonvulsant effective in the treatment of affective illness, caused a reduction in the TSH response to TRH. This finding suggests that carbamazepine may decrease thyroid function primarily at the level of the pituitary in affectively ill patients.Entities:
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Year: 1984 PMID： 6433372 DOI： 10.1016/0165-1781(84)90016-7
Source DB: PubMed Journal: Psychiatry Res ISSN： 0165-1781 Impact factor: 3.222