Literature DB >> 6433306

Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks.

D A Dobbelaere, P R Spooner, W C Barry, A D Irvin.   

Abstract

Monoclonal antibodies were raised against sporozoites of Theileria parva. One of these antibodies (MAbD1) neutralized the infectivity of sporozoites for lymphocytes in vitro and for cattle in vivo. Neutralization seemed to occur by blocking sporozoite entry into the cell. MAbD1 neutralized sporozoites of four unrelated stocks of T. parva, indicating the presence of a common antigenic determinant which may be important in initiating protective immunity.

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Year:  1984        PMID： 6433306     DOI： 10.1111/j.1365-3024.1984.tb00808.x

Source DB:  PubMed          Journal:  Parasite Immunol        ISSN： 0141-9838            Impact factor:   2.280


  23 in total

1.  Theileria annulata sporozoite surface antigen expressed in Escherichia coli elicits neutralizing antibody.

Authors:  S Williamson; A Tait; D Brown; A Walker; P Beck; B Shiels; J Fletcher; R Hall
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

2.  Comparative analysis of infection and transformation of lymphocytes from African buffalo and Boran cattle with Theileria parva subsp. parva and T. parva subsp. lawrencei.

Authors:  C L Baldwin; M N Malu; S W Kinuthia; P A Conrad; J G Grootenhuis
Journal:  Infect Immun       Date:  1986-07       Impact factor: 3.441

3.  A Theileria parva isolate of low virulence infects a subpopulation of lymphocytes.

Authors:  Heshborne S Tindih; Dirk Geysen; Bruno M Goddeeris; Elias Awino; Dirk A E Dobbelaere; Jan Naessens
Journal:  Infect Immun       Date:  2011-12-27       Impact factor: 3.441

4.  Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle.

Authors:  V Nene; S Inumaru; D McKeever; S Morzaria; M Shaw; A Musoke
Journal:  Infect Immun       Date:  1995-02       Impact factor: 3.441

5.  Identification of lambda gt11 clones encoding the major antigenic determinants expressed by Theileria parva sporozoites.

Authors:  K P Iams; R Hall; P Webster; A J Musoke
Journal:  Infect Immun       Date:  1990-06       Impact factor: 3.441

6.  Conservation of the sporozoite p67 vaccine antigen in cattle-derived Theileria parva stocks with different cross-immunity profiles.

Authors:  V Nene; A Musoke; E Gobright; S Morzaria
Journal:  Infect Immun       Date:  1996-06       Impact factor: 3.441

7.  Phenotypic characterization of Theileria parva schizonts by two-dimensional gel electrophoresis.

Authors:  C Sugimoto; P A Conrad; L Mutharia; T T Dolan; W C Brown; B M Goddeeris; T W Pearson
Journal:  Parasitol Res       Date:  1989       Impact factor: 2.289

8.  Role of the polymorphic immunodominant molecule in entry of Theileria parva sporozoites into bovine lymphocytes.

Authors:  Philip Toye; Antony Musoke; Jan Naessens
Journal:  Infect Immun       Date:  2014-02-18       Impact factor: 3.441

9.  A recombinant sporozoite surface antigen of Theileria parva induces protection in cattle.

Authors:  A Musoke; S Morzaria; C Nkonge; E Jones; V Nene
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-15       Impact factor: 11.205

10.  Identification of a surface antigen on Theileria parva sporozoites by monoclonal antibody.

Authors:  D A Dobbelaere; S Z Shapiro; P Webster
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205
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