Literature DB >> 6432928

The cyclo-oxygenase and lipoxygenase pathways in human oral cancer tissue.

H Porteder, M Matejka, W Ulrich, H Sinzinger.   

Abstract

This paper reports on the synthesis of prostaglandins in oral squamous epithelial carcinomas. Using radio-thin-layer chromatography, we observed the conversion of 14C-labelled arachidonic acid into the prostaglandins PGE2, PGF2 alpha, PGI2 and PGD2. We also observed an approximately equal production of hydroxy fatty acids. The role of the above-mentioned substances in the growth of malignant tumours and the process of metastasis is discussed.

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Year:  1984        PMID： 6432928     DOI： 10.1016/s0301-0503(84)80234-9

Source DB:  PubMed          Journal:  J Maxillofac Surg        ISSN： 0301-0503


  5 in total

1.  Effects of leukotrienes on osteoblastic cell proliferation.

Authors:  W Ren; R Dziak
Journal:  Calcif Tissue Int       Date:  1991-09       Impact factor: 4.333

Review 2.  Regulation of inflammation by lipid mediators in oral diseases.

Authors:  S Sommakia; O J Baker
Journal:  Oral Dis       Date:  2016-08-04       Impact factor: 3.511

3.  Macromolecular osteolytic factor synthesised by squamous carcinoma cell lines from the head and neck in vitro is interleukin 1.

Authors:  S Meghji; J R Sandy; A M Scutt; W Harvey; R L Carter; M Harris
Journal:  Br J Cancer       Date:  1988-07       Impact factor: 7.640

4.  A possible role for leukotriene B4 in head and neck cancer.

Authors:  I el-Hakim; J Zakrzewski; J Langdon; P Piper; J Costello
Journal:  Br J Cancer       Date:  1989-05       Impact factor: 7.640

5.  Acetylsalicylic acid (ASA) protects the prostaglandin-cAMP-system of human hypernephroma cells against irradiation-induced alterations.

Authors:  S R Li; Q Yang; E Wandl; W Pirker; I Virgolini
Journal:  Br J Cancer       Date:  1993-10       Impact factor: 7.640
  5 in total

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