Literature DB >> 6432894

The growth hormone responses to L-dopa and TRH in acromegaly.

I Jialal, C Naidoo, B C Nathoo, M C Rajput, S M Joubert.   

Abstract

The GH responses to TRH and L-dopa were investigated in 14 Indian and African patients with untreated acromegaly. A positive response to L-dopa (greater than 50% change from basal) was obtained in 6 of the 14 patients tested while a positive response to TRH (greater than 100% change from basal) was found in 5 of 12 patients tested. While 9 patients responded to at least one agent, only 2 had a positive response to both agents. Positive responders appeared to be hyper-prolactinemic and have evidence of abnormal glucose tolerance as compared to nonresponders.

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Year:  1984        PMID： 6432894     DOI： 10.1007/BF03348430

Source DB:  PubMed          Journal:  J Endocrinol Invest        ISSN： 0391-4097            Impact factor:   4.256


  10 in total

1.  Somatostatin sensitivity and growth hormone responses to releasing hormones and bromocryptine in acromegaly.

Authors:  G F Pieters; J E Romeijn; A G Smals; P W Kloppenborg
Journal:  J Clin Endocrinol Metab       Date:  1982-05       Impact factor: 5.958

2.  The spectrum of pituitary growth hormone responses to pharmacological stimuli in acromegaly.

Authors:  K Hanew; M Kokubun; A Sasaki; T Mouri; K Yoshinaga
Journal:  J Clin Endocrinol Metab       Date:  1980-08       Impact factor: 5.958

3.  WHO Expert Committee on Diabetes Mellitus: second report.

Authors: 
Journal:  World Health Organ Tech Rep Ser       Date:  1980

Review 4.  Diseases of the hypothalamus and pituitary gland.

Authors:  C R Edwards; G M Besser
Journal:  Clin Endocrinol Metab       Date:  1974-11

5.  Increase of serum growth hormone concentration following thyrotropin-releasing hormone injection in patients with acromegaly or gigantism.

Authors:  M Irie; T Tsushima
Journal:  J Clin Endocrinol Metab       Date:  1972-07       Impact factor: 5.958

6.  Pituitary function in Sheehan's syndrome.

Authors:  I Jialal; C Naidoo; R J Norman; M C Rajput; M A Omar; S M Joubert
Journal:  Obstet Gynecol       Date:  1984-01       Impact factor: 7.661

7.  The value of plasma prolactin levels in the prediction of the responsiveness of growth hormone secretion to bromocriptine and TRH in acromegaly.

Authors:  S W Lamberts; A Liuzzi; P G Chiodini; S Verde; J G Klijn; J C Birkenhäger
Journal:  Eur J Clin Invest       Date:  1982-04       Impact factor: 4.686

8.  The clinical presentation and biochemical diagnosis of acromegaly and gigantism.

Authors:  I Jialal; B C Nathoo; S Joubert; A C Asmal; N L Pillay
Journal:  S Afr Med J       Date:  1982-04-24

9.  Hypopituitarism. A 3-year study.

Authors:  I Jialal; N L Pillay; A C Asmal; J A Naidoo
Journal:  S Afr Med J       Date:  1981-04-18

10.  Growth hormone (GH)-releasing activity of TRH and GH-lowering effect of dopaminergic drugs in acromegaly: homogeneity in the two responses.

Authors:  A Liuzzi; P G Chiodini; L Botalla; F Silvestrini; E E Müller
Journal:  J Clin Endocrinol Metab       Date:  1974-11       Impact factor: 5.958
  10 in total
  1 in total

1.  Effects of intravenous TRH on growth hormone and cortisol serum levels in children and adolescents with insulin dependent diabetes mellitus.

Authors:  M Vanelli; S Bernasconi; O Bolondi; C Mamì; E Pandullo; M Scaffidi; M F Siracusano; F De Luca
Journal:  J Endocrinol Invest       Date:  1986-08       Impact factor: 4.256
  1 in total

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