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Literature DB >> 6432419

The effects of auranofin and parenteral gold in the treatment of rheumatoid arthritis: an X-ray analysis.

Abstract

X-rays from patients in comparative studies of auranofin and parenteral gold were obtained before and during treatment, and analysed using a modification of the method of Larsen. One hundred and nineteen auranofin-treated and 113 parenteral gold-treated patients contributed data, which were analysed for changes from 0-6 months, 0-12 months and from 0-6 and 12 months. Progression of erosive processes and of joint grade occurred with both treatments, but the proportion of patients with progression in the first six months was greater with auranofin treatment. However, there was evidence that both treatments produced slowing of the erosive process during the second six months of treatment.

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Year: 1984 PMID： 6432419 DOI： 10.1007/bf03342627

Source DB: PubMed Journal: Clin Rheumatol ISSN： 0770-3198 Impact factor: 2.980

13 in total

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Authors:
Journal: Ann Rheum Dis Date: 1959-09 Impact factor: 19.103

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Authors:
Journal: Ann Rheum Dis Date: 1957-09 Impact factor: 19.103

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Authors:
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Authors: A Larsen; K Dale; M Eek
Journal: Acta Radiol Diagn (Stockh) Date: 1977-07

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Authors: T Gibson; E C Huskisson; J A Wojtulewski; P J Scott; H W Balme; H C Burry; R Grahame; F D Hart
Journal: Rheumatol Rehabil Date: 1976-08

Review 7. Does drug therapy slow radiographic deterioration in rheumatoid arthritis?

Authors: L Iannuzzi; N Dawson; N Zein; I Kushner
Journal: N Engl J Med Date: 1983-10-27 Impact factor: 91.245

8. Chrysotherapy in rheumatoid arthritis with particular emphasis on the effect of chrysotherapy on radiographical changes and on the optimal time of initiation of therapy.

Authors: R Luukkainen
Journal: Scand J Rheumatol Suppl Date: 1980

9. Radiographic evaluation of erosion in rheumatoid arthritis: double blind study of auranofin vs placebo.

Authors: J P Gofton; W M O'Brien; J N Hurley; B J Scheffler
Journal: J Rheumatol Date: 1984-12 Impact factor: 4.666

10. Gold salts in the treatment of rheumatoid arthritis. A double-blind study.

Authors: J W Sigler; G B Bluhm; H Duncan; J T Sharp; D C Ensign; W R McCrum
Journal: Ann Intern Med Date: 1974-01 Impact factor: 25.391

7 in total

1. Prospective six year follow up of patients withdrawn from a randomised study comparing parenteral gold salt and methotrexate.

Authors: O Sander; G Herborn; E Bock; R Rau
Journal: Ann Rheum Dis Date: 1999-05 Impact factor: 19.103

The effects of auranofin and parenteral gold in the treatment of rheumatoid arthritis: an X-ray analysis.

1. A COMPARISON of prednisolone with aspirin on other analgesics in the treatment of rheumatold rthritis.

2. EMPIRE Rheumatism Council: multi-centre controlled trial comparing cortisone acetate and acetyl salicylic acid in the long-term treatment of rheumatoid arthritis; results of three years' treatment.

3. Gold Therapy in Rheumatoid Arthritis: Final Report of a Multicentre Controlled Trial.

4. Gold therapy in early rheumatoid arthritis.

5. Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films.

6. Evidence that D-penicillamine alters the course of rheumatoid arthritis.

Review 7. Does drug therapy slow radiographic deterioration in rheumatoid arthritis?

8. Chrysotherapy in rheumatoid arthritis with particular emphasis on the effect of chrysotherapy on radiographical changes and on the optimal time of initiation of therapy.

9. Radiographic evaluation of erosion in rheumatoid arthritis: double blind study of auranofin vs placebo.

10. Gold salts in the treatment of rheumatoid arthritis. A double-blind study.

1. Prospective six year follow up of patients withdrawn from a randomised study comparing parenteral gold salt and methotrexate.

Review 2. Worldwide clinical experience with auranofin.

3. A three year comparative study of auranofin and gold sodium thiomalate in rheumatoid arthritis.

Review 4. Have traditional DMARDs had their day? Effectiveness of parenteral gold compared to biologic agents.

5. Precision of Larsen grading of radiographs in assessing progression of rheumatoid arthritis in individual patients.

Review 6. Disease-modifying antirheumatic drugs. Potential effects in older patients.

7. Contribution of patient related differences to multidrug resistance in rheumatoid arthritis.