| Literature DB >> 6432295 |
A M Yaari, A L Boskey, I M Shapiro.
Abstract
The ionophoretic activities of a stable Ca-PS-Pi complex were examined in a three-compartment lipid-aqueous phase transport system. It was found that the complex transported Ca2+ at a slower rate than free PS. Analysis of the transport process, using an equilibrium partitioning model, revealed that Ca2+ binding to the complex was the rate-limiting step. This inhibition was overcome by the addition of exogeneous Pi. It was concluded that the complex acted as an ionophore and that the presence of coordinated Ca and P atoms facilitated Pi modulation of Ca2+ transport.Entities:
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Year: 1984 PMID： 6432295 DOI： 10.1007/bf02405336
Source DB: PubMed Journal: Calcif Tissue Int ISSN： 0171-967X Impact factor: 4.333