| Literature DB >> 6431403 |
J Shipley, C H Rodeck, C Garrett, J Galbraith, F Giannelli.
Abstract
We report the use of fetal blood for the prenatal diagnosis of Fanconi anaemia (FA). The clastogenic action of Mitomycin C (MMC) is compared in blood cultures from different fetuses, normal controls and FA heterozygotes. The fetus at risk is shown to suffer from FA on the grounds of excessive chromosome breakage, both spontaneous and MMC induced.Entities:
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Year: 1984 PMID： 6431403 DOI： 10.1002/pd.1970040310
Source DB: PubMed Journal: Prenat Diagn ISSN： 0197-3851 Impact factor: 3.050