Literature DB >> 6431056

Relationship between the circulating levels of adenohypophyseal hormones in blood and in cerebrospinal fluid.

A Nicolini, R Buonaguidi, M Ferdeghini, A Carpi.   

Abstract

Concentrations of prolactin, follicle stimulating hormone, luteinising hormone and growth hormone were measured simultaneously in the serum and cerebrospinal fluid of 57 patients affected by neurologic disease without any pituitary or diencephalic involvement. Prolactin secretion was stimulated in another group of 12 patients using sulpiride or metoclopramide, and the hormone concentration was measured simultaneously in serum and in CSF during the test. Basal studies showed that the concentrations of prolactin, FSH, LH and GH in serum and in CSF were directly correlated (p varying from less than 0.001 to less than 0.05). A negative correlation was found between the molecular weight of hormones reported in this and in other studies and the natural logarithm of the CSF/serum hormone concentration ratios. During prolactin stimulation the correlation between serum and CSF concentration was maintained, nevertheless a higher increase of prolactin in blood than in CSF was observed. This last finding suggests that other mechanisms in addition to filtration from blood into CSF can be responsible for the presence of adenohypophyseal hormones in CSF.

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Year:  1984        PMID: 6431056      PMCID: PMC1027899          DOI: 10.1136/jnnp.47.7.710

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  22 in total

1.  Immunoreactive ACTH in cerebrospinal fluid.

Authors:  J P Allen; J W Kendall; R McGilvra; C Vancura
Journal:  J Clin Endocrinol Metab       Date:  1974-04       Impact factor: 5.958

2.  Protein size and cerebrospinal fluid composition.

Authors:  K Felgenhauer
Journal:  Klin Wochenschr       Date:  1974-12-15

3.  Corticotrophin in cerebrospinal fluid of patients with Nelson's syndrome.

Authors:  M Kleerekoper; R A Donald; S Posen
Journal:  Lancet       Date:  1972-01-08       Impact factor: 79.321

4.  Insulin in the cerebro spinal fluid of man.

Authors:  A V Greco; G Ghirlanda; G Fedeli; G Gambassi
Journal:  Eur Neurol       Date:  1970       Impact factor: 1.710

5.  The relationship between blood and cerebrospinal fluid prolactin in nonhuman primates.

Authors:  N H Kalin; R S Burns; S C Risch; S A Cosgrove; D Warden; D L Murphy
Journal:  Life Sci       Date:  1982-07-12       Impact factor: 5.037

6.  Cerebrospinal fluid prolactin: a reflection of abnormal prolactin secretion in patients with pituitary tumors.

Authors:  L L Schroeder; J C Johnson; W B Malarkey
Journal:  J Clin Endocrinol Metab       Date:  1976-12       Impact factor: 5.958

7.  Immunoreactive beta-melanocyte-stimulating hormone in cerebrospinal fluid.

Authors:  A G Smith; S Shuster
Journal:  Lancet       Date:  1976-06-19       Impact factor: 79.321

8.  Distribution of growth hormone and thyroid-stimulating hormone in cerebrospinal fluid and pathological compartments of the central nervous system.

Authors:  C Schaub; M T Bluet-Pajot; G Szikla; C Lornet; J Talairach
Journal:  J Neurol Sci       Date:  1977 Jan-Feb       Impact factor: 3.181

9.  Immunodiagnosis and monitoring of gonadotrophin-producing metastases in the central nervous system.

Authors:  K D Bagshawe; S Harland
Journal:  Cancer       Date:  1976-07       Impact factor: 6.860

10.  Cerebrospinal fluid hormone concentration in the evaluation of pituitary tumors.

Authors:  R M Jordan; J W Kendall; J L Seaich; J P Allen; C A Paulsen; C W Kerber; W P Vanderlaan
Journal:  Ann Intern Med       Date:  1976-07       Impact factor: 25.391

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  1 in total

1.  Anterior Pituitary Hormones in Blood and Cerebrospinal Fluid of Patients in Neurocritical Care.

Authors:  Henriette Beyer; Nicole Lange; Armin H Podtschaske; Jan Martin; Lucia Albers; Alexander von Werder; Jürgen Ruland; Gerhard Schneider; Bernhard Meyer; Simone M Kagerbauer; Jens Gempt
Journal:  touchREV Endocrinol       Date:  2022-06-13
  1 in total

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