Literature DB >> 6429904

Effect of aflatoxin B1 on brain serotonin and catecholamines in chickens.

N Ahmed, U S Singh.   

Abstract

A single oral dose of aflatoxin B1 at 3 mg/kg body weight caused a significant increase in brain serotonin (5-HT) in 5-week-old chickens. Norepinephrine (NE) brain concentration significantly decreased, whereas the dopamine (DA) concentration remained unchanged. These results suggest that in modifying the concentrations of biogenic amines in the brain, aflatoxin B1 may affect brain function.

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Year:  1984        PMID： 6429904     DOI： 10.1016/0378-4274(84)90098-5

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN： 0378-4274            Impact factor:   4.372


  4 in total

1.  The effect of aflatoxin B1 exposure on serotonin metabolism: response to a tryptophan load.

Authors:  T D Kimbrough; G C Llewellyn; L B Weekley
Journal:  Metab Brain Dis       Date:  1992-12       Impact factor: 3.584

2.  Effect of deoxynivalenol on neurotransmitters in discrete regions of swine brain.

Authors:  D B Prelusky; J M Yeung; B K Thompson; H L Trenholm
Journal:  Arch Environ Contam Toxicol       Date:  1992-01       Impact factor: 2.804

3.  Aflatoxin B1 alters central and systemic tryptophan and tyrosine metabolism: influence of immunomodulatory drugs.

Authors:  L B Weekley
Journal:  Metab Brain Dis       Date:  1991-03       Impact factor: 3.584

4.  Alteration of biogenic amines in mouse brain regions by alkylating agents. I. Effects of aflatoxin B1 on brain monoamines concentrations and activities of metabolizing enzymes.

Authors:  S Jayasekara; D B Drown; R A Coulombe; R P Sharma
Journal:  Arch Environ Contam Toxicol       Date:  1989 May-Jun       Impact factor: 2.804
  4 in total

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