| Literature DB >> 6429564 |
S Laurian, J M Gaillard, P K Le, J Schöpf.
Abstract
Brain electrical activity changes induced by Ro 15-1788, an antagonist of central benzodiazepine effects, were investigated in 10 normal subjects. The diazepam-induced sedation, as ascertained by spontaneous EEG, was rapidly reversed after an intravenous injection of 5 mg Ro 15-1788. There appeared to be a good correlation between the EEG and evoked responses modifications; the decrease of the amplitude of the N2 wave may reflect an increase of alertness.Entities:
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Year: 1984 PMID： 6429564 DOI： 10.1159/000118052
Source DB: PubMed Journal: Neuropsychobiology ISSN： 0302-282X Impact factor: 2.328